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Product Info Summary
| SKU: | A00212 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-IL-15 Antibody
SKU/Catalog Number
A00212
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IL-15 Antibody (Catalog # A00212). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
IL-15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-IL-15 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00212)
Host
Rabbit
Contents
IL-15 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15. The immunogen is located within amino acids 50 - 100 of IL-15.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of IL-15 are known to exist.
Reactive Species
A00212 is reactive to IL15 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
18086 MW
Background of IL-15
Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00212 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IL-15 antibody can be used for detection of IL-15 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IL-15 in rat spleen tissue lysate with IL-15 antibody at (A) 1 and (B) 2 μg/mL
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Immunohistochemistry of IL-15 in human spleen tissue with IL-15 antibody at 2.5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For IL15 (Source: Uniprot.org, NCBI)
Gene Name
IL15
Full Name
Interleukin-15
Weight
18086 MW
Superfamily
IL-15/IL-21 family
Alternative Names
IL-15, Interleukin-15, IL-15 IL15 IL-15 interleukin 15 interleukin-15
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL15, check out the IL15 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL15: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL-15 Antibody (A00212)
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No publications found for A00212
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