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Product Info Summary
| SKU: | RP1028 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-IL12 p40/IL12B Antibody Picoband®
SKU/Catalog Number
RP1028
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-IL12 p40/IL12B Antibody catalog # RP1028. Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-IL12 p40/IL12B Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1028)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
E.coli-derived rat IL-12 (p40) recombinant protein (Position: M23-S321).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
RP1028 is reactive to IL12B in Rat
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
20 kDa
Calculated molecular weight
38413 MW
Background of Il12b
Subunit beta of interleukin 12, also known as interleukin 12B, or IL12B, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
RP1028 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Rat
Validation Images & Assay Conditions
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Anti-IL-12(p40) Picoband antibody, RP1028
All lanes: Anti-IL-12(p40)(RP1028) at 0.5ug/ml
WB: Recombinant Rat IL-12(p40) Protein 0.5ng
Predicted bind size: 20KD
Observed bind size: 20KD
Protein Target Info & Infographic
Gene/Protein Information For IL12B (Source: Uniprot.org, NCBI)
Gene Name
IL12B
Full Name
Interleukin-12 subunit beta
Weight
38413 MW
Superfamily
IL-12B family
Alternative Names
Interleukin-12 subunit beta ;Cytotoxic lymphocyte maturation factor 40 kDa subunit ;IL-12 subunit p40 ;Il12b ;IL12B ; IL12B CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2 interleukin 12B interleukin-12 subunit beta|CLMF p40|IL-12 subunit p40|IL12, subunit p40|NK cell stimulatory factor chain 2|cytotoxic lymphocyte maturation factor 40 kDa subunit|interleukin 12, p40|interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)|interleukin-12 beta chain|natural killer cell stimulatory factor, 40 kD subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL12B, check out the IL12B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL12B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL12 p40/IL12B Antibody Picoband® (RP1028)
Hello CJ!
RP1028 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Anti-arthritis activity of cationic materials
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-IL12 p40/IL12B Antibody Picoband®
Question
We are currently using anti-IL12 p40/IL12B antibody RP1028 for rat tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says rat. Is it possible that the antibody can work on primate tissues as well?
Verified Customer
Verified customer
Asked: 2019-01-17
Answer
The anti-IL12 p40/IL12B antibody (RP1028) has not been tested for cross reactivity specifically with primate tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-01-17
