Anti-IF3 MTIF3 Antibody

Product Name

Anti-IF3 MTIF3 Antibody

View all Mitocondrial Translational Initiation Factor 3 Antibodies

SKU/Catalog Number

A11221

Size

100μl

Form

Liquid

Description

Boster Bio Anti-IF3 MTIF3 Antibody catalog # A11221. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IF3 MTIF3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11221)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human IF3. at AA rangle: 40-120

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A11221 is reactive to Mtif3 in Human

Applications

A11221 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

31725 MW

Background of Mitocondrial Translational Initiation Factor 3

Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).

Wiedenmann, B. et al. (1986) Proc Natl Acad Sci USA 83, 3500-4.
Valtorta, F. et al. (2004) Bioessays 26, 445-53.
Arthur, C.P. and Stowell, M.H. (2007) Structure 15, 707-14.
Bonanomi, D. et al. (2007) Biochem J 404, 525-34.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of HuvEc cells using IF3 Polyclonal antibody.

Gene/Protein Information For Mtif3 (Source: Uniprot.org, NCBI)

Alternative Names

FLJ33676; IF3(mt); IF-3mt; mitochondrial translational initiation factor 3; mitochondrial

For more info on Mtif3, check out the Mtif3 Infographic

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In this infographic, you will see the following information for Mtif3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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