Product Info Summary
SKU: | FC01281-FITC |
---|---|
Size: | 100 tests, 200 tests |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry |
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Product info
Product Name
Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated
SKU/Catalog Number
FC01281-FITC
Size
100 tests, 200 tests
Form
Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA
Description
Boster Bio Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated (Catalog# FC01281-FITC). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC01281-FITC)
Host
Mouse
Contents
PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide
Clonality
Monoclonal
Clone Number
Clone: 1D6
Isotype
IgG1,k
Immunogen
5A6 aggregated OCI-Ly8 human B cell line
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
FC01281-FITC is reactive to CD81 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
25809 MW
Background of CD81
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. And this protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
FC01281-FITC is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
User needs to optimize the dilution ratio for this antibody.
Validation Images & Assay Conditions
Click image to see more details
Lymphocytes gated whole blood stained with FITC conjugated anti-human CD81 (clone 1D6) followed by RBC lysis (red histogram). Lymphocytes gated whole blood stained with FITC conjugated mouse IgG1 (clone MOPC-31) isotype control followed by RBC lysis (Blue histogram). The data are generated by BD Accuri C6 Flow Cytometer and analyzed by FlowJo software.
Protein Target Info & Infographic
Gene/Protein Information For CD81 (Source: Uniprot.org, NCBI)
Gene Name
CD81
Full Name
CD81 antigen
Weight
25809 MW
Superfamily
tetraspanin (TM4SF) family
Alternative Names
CD81 antigen;26 kDa cell surface protein TAPA-1;Target of the antiproliferative antibody 1;Tetraspanin-28;Tspan-28;CD81;CD81;TAPA1, TSPAN28; CD81 CVID6, S5.7, TAPA1, TSPAN28 CD81 molecule CD81 |26 kDa cell surface protein TAPA-1|CD81 (target of antiproliferative 1)|tetraspanin-28|tspan-28
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD81, check out the CD81 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD81: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated (FC01281-FITC)
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Customer Q&As
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3 Customer Q&As for Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated
Question
Is this FC01281-FITC anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated reactive to the isotypes of CD81?
Verified Customer
Verified customer
Asked: 2019-01-07
Answer
The immunogen of FC01281-FITC anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated is 5A6 aggregated OCI-Ly8 human B cell line. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2019-01-07
Question
We want to test anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated FC01281-FITC on human myometrium for research purposes, then I may be interested in using anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated FC01281-FITC for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
L. Baker
Verified customer
Asked: 2016-09-13
Answer
The products we sell, including anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated FC01281-FITC, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2016-09-13
Question
I was wanting to use your anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated for Flow Cytometry for human myometrium on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human myometrium identification?
S. Johnson
Verified customer
Asked: 2014-05-13
Answer
It shows on the product datasheet, FC01281-FITC anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated has been validated for Flow Cytometry on human tissues. We have an innovator award program that if you test this antibody and show it works in human myometrium in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2014-05-13