Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated

CD81 antibody

Boster Bio Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated (Catalog# FC01281-FITC). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Product Info Summary

SKU: FC01281-FITC
Size: 100 tests, 200 tests
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry

Product Name

Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated

View all CD81 Antibodies

SKU/Catalog Number

FC01281-FITC

Size

100 tests, 200 tests

Form

Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA

Description

Boster Bio Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated (Catalog# FC01281-FITC). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC01281-FITC)

Host

Mouse

Contents

PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide

Clonality

Monoclonal

Clone Number

Clone: 1D6

Isotype

IgG1,k

Immunogen

5A6 aggregated OCI-Ly8 human B cell line

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

FC01281-FITC is reactive to CD81 in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

25809 MW

Background of CD81

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. And this protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

FC01281-FITC is guaranteed for Flow Cytometry Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

User needs to optimize the dilution ratio for this antibody.

Validation Images & Assay Conditions

Gene/Protein Information For CD81 (Source: Uniprot.org, NCBI)

Gene Name

CD81

Full Name

CD81 antigen

Weight

25809 MW

Superfamily

tetraspanin (TM4SF) family

Alternative Names

CD81 antigen;26 kDa cell surface protein TAPA-1;Target of the antiproliferative antibody 1;Tetraspanin-28;Tspan-28;CD81;CD81;TAPA1, TSPAN28; CD81 CVID6, S5.7, TAPA1, TSPAN28 CD81 molecule CD81 |26 kDa cell surface protein TAPA-1|CD81 (target of antiproliferative 1)|tetraspanin-28|tspan-28

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CD81, check out the CD81 Infographic

CD81 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CD81: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-Human CD81 Monoclonal Antibody FITC Conjugated, Flow Validated

Question

Is this FC01281-FITC anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated reactive to the isotypes of CD81?

Verified Customer

Verified customer

Asked: 2019-01-07

Answer

The immunogen of FC01281-FITC anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated is 5A6 aggregated OCI-Ly8 human B cell line. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2019-01-07

Question

We want to test anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated FC01281-FITC on human myometrium for research purposes, then I may be interested in using anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated FC01281-FITC for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

L. Baker

Verified customer

Asked: 2016-09-13

Answer

The products we sell, including anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated FC01281-FITC, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2016-09-13

Question

I was wanting to use your anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated for Flow Cytometry for human myometrium on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human myometrium identification?

S. Johnson

Verified customer

Asked: 2014-05-13

Answer

It shows on the product datasheet, FC01281-FITC anti-Human CD81 Monoclonal antibody FITC Conjugated, Flow Validated has been validated for Flow Cytometry on human tissues. We have an innovator award program that if you test this antibody and show it works in human myometrium in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2014-05-13

Order DetailsPrice
FC01281-FITC-100tests

100 tests

$235
FC01281-FITC-200tests

200 tests

$358

Free Secondary Antibody

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FC01281-FITC
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$235.00

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