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Product Info Summary
| SKU: | FC00193 |
|---|---|
| Size: | 100ug, 500ug |
| Reactive Species: | Cynomolgus monkey, Human, Baboon, Rhesus monkey |
| Host: | Mouse |
| Application: | Flow Cytometry |
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Product info
Product Name
Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated
SKU/Catalog Number
FC00193
Size
100ug, 500ug
Form
Liquid
Description
Boster Bio Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated (Catalog# FC00193). Tested in Flow Cytometry application(s). This antibody reacts with Human, Rhesus monkey, Cynomolgus monkey, Baboon.
Storage & Handling
Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00193)
Host
Mouse
Contents
PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide
Clonality
Monoclonal
Clone Number
Clone: OKT10
Isotype
IgG1,k
Immunogen
Human acute lymphoblastic leukaemia cells
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
FC00193 is reactive to CD38 in Cynomolgus monkey, Human, Baboon, Rhesus monkey
Reconstitution
Calculated molecular weight
34328 MW
Background of CD38
ITGAM (Integrin Alpha-M), also called CD11B or Mo1 ALPHA SUBUNIT (MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3 (CR3A; also called ITGAM, Mac1, or Mo1), lymphocyte function-associated (LFA) antigen type 1 (ITGAL), and p150, 95 (ITGAX). By in situ hybridization, Corbi et al. (1988) demonstrated that the genes encoding the alpha subunits of LFA1 (ITGAL), Mac1, and p150, 95 (ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et al. (1991) narrowed the assignment to 16p11.2. Inflammation plays an essential role in the initiation and progression of atherosclerosis. Simon et al. (2000) presented evidence that it also has a role in vascular repair after mechanical arterial injury (i.e., percutaneous transluminal coronary angioplasty, or PTCA).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
FC00193 is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
User needs to optimize the dilution ratio for this antibody.
Validation Images & Assay Conditions
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Lymphocytes gated PBMCs stained with purified anti-human CD38 (clone OKT-10) followed by Goat anti-mouse IgG (H+L) Alexa Fluor 488 (red histogram). PBMCs monocytes stained with only Goat antimouse IgG (H+L) Alexa Fluor 488 (Blue histogram).
Protein Target Info & Infographic
Gene/Protein Information For CD38 (Source: Uniprot.org, NCBI)
Gene Name
CD38
Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Weight
34328 MW
Superfamily
ADP-ribosyl cyclase family
Alternative Names
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;3.2.2.6;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2.4.99.20;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADPRC 1;Cyclic ADP-ribose hydrolase 1;cADPr hydrolase 1;T10;CD38;CD38; CD38 ADPRC 1, ADPRC1 CD38 molecule ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|2-phospho-ADP-ribosyl cyclase|2-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|CD38 (p45)|NAD(+) nucleosidase|cluster of differentiation 38|cyclic ADP-ribose hydrolase 1|ecto-nicotinamide adenine dinucleotide glycohydrolase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD38, check out the CD38 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD38: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated (FC00193)
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No publications found for FC00193
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