Anti-Hu CD203c Purified ENPP3 Monoclonal Antibody

Product Name

Anti-Hu CD203c Purified ENPP3 Monoclonal Antibody

View all ENPP-3/CD203c Antibodies

SKU/Catalog Number

M05615

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD203c Purified ENPP3 Monoclonal Antibody (Catalog# M05615). Tested in Flow Cytometry, ICC application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD203c Purified ENPP3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M05615)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

NP4D6

Isotype

Mouse IgG1

Immunogen

HEK-293 cells transfected with human CD203c. The mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody does not cross-react with Thy-1.1 alloantigen.

Reactive Species

M05615 is reactive to ENPP3 in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

100124 MW

Background of ENPP-3/CD203c

CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M05615 is guaranteed for Flow Cytometry, ICC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml. Extracellular and intracellular staining.

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For ENPP3 (Source: Uniprot.org, NCBI)

Alternative Names

ENPP3, B10, PDNP3, PD-IBETA ENPP3 B10, CD203c, NPP3, PD-IBETA, PDNP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 ectonucleotide pyrophosphatase/phosphodiesterase family member 3|dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)|dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)|gp130RB13-6|phosphodiesterase I/nucleotide pyrophosphatase 3|phosphodiesterase-I beta

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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