Anti-HRG Antibody Picoband®

Product Name

Anti-HRG Antibody Picoband®

View all HPRG Antibodies

SKU/Catalog Number

PB9220

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-HRG Antibody Picoband® catalog # PB9220. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HRG Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9220)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human HRG recombinant protein (Position: V19-V200). Human HRG shares 71% and 69% amino acid (aa) sequences identity with mouse and rat HRG, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9220 is reactive to HRG in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

60 kDa

Calculated molecular weight

59578 MW

Background of HPRG

Histidine-rich glycoprotein (HRG) is a protein that in humans is encoded by the HRG gene. It is mapped to 3q27.3. HRG contains two cystatin-like domains and is located in plasma and platelets. The protein can bind heme, dyes and divalent metal ions. It also can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. HRG is thought to have multiple roles as a protein in the human blood, including roles in immunity, angiogenesis and coagulation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PB9220 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: Human Placenta Tissue
IHC: Human Intestinal Cancer Tissue

Validation Images & Assay Conditions

Gene/Protein Information For HRG (Source: Uniprot.org, NCBI)

Alternative Names

Histidine-rich glycoprotein;Histidine-proline-rich glycoprotein;HPRG;HRG; HRG HPRGP, THPH11, HRG histidine rich glycoprotein histidine-rich glycoprotein|histidine-proline-rich glycoprotein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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