Key=store_id
Key=entity_id, value=2568
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Key=type_id, value=simple
Key=sku, value=PB9220
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2014-04-13 19:10:46
Key=updated_at, value=2024-09-26 00:46:14
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-HRG Antibody Picoband®
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Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
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Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Rabbit
Key=quantity_and_stock_status
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1365
Key=yoast_content_score, value=60
Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-HRG Antibody Picoband® | Bosterbio
Key=meta_description, value=Boster Bio Anti-HRG Antibody Picoband® catalog # PB9220. Tested in IHC, WB applications. This antibody reacts with Human. Supplied as 100μg/vial in Lyophilized form antibody.
Key=image, value=/p/b/pb9220-1.jpg
Key=small_image, value=/p/b/pb9220-1.jpg
Key=thumbnail, value=/p/b/pb9220-1.jpg
Key=url_key, value=anti-hrg-picoband-trade-antibody-pb9220-boster
Key=url_path, value=anti-hrg-picoband-trade-antibody-pb9220-boster
Key=options_container, value=Product Info Column
Key=image_label, value=Anti- HRG antibody, PB9220, Western blotting
All lanes: Anti HRG (PB9220) at 0.5ug/ml
WB: Recombinant Human HRG Protein 0.5ng
Predicted bind size: 40KD
Observed bind size: 40KD
Key=small_image_label, value=Anti- HRG antibody, PB9220, Western blotting
All lanes: Anti HRG (PB9220) at 0.5ug/ml
WB: Recombinant Human HRG Protein 0.5ng
Predicted bind size: 40KD
Observed bind size: 40KD
Key=thumbnail_label, value=Anti- HRG antibody, PB9220, Western blotting
All lanes: Anti HRG (PB9220) at 0.5ug/ml
WB: Recombinant Human HRG Protein 0.5ng
Predicted bind size: 40KD
Observed bind size: 40KD
Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=100 μg/vial
Key=protein_name, value=Histidine-rich glycoprotein
Key=gene_full_name, value=Histidine-rich glycoprotein
Key=uniprot_id, value=P04196
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=IHC, WB
Key=reactivity, value=Human
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Key=predicted_reactivity
Key=source_company, value=Boster PB9220
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=59578 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cancer, Neural Signal Transduction, Neurology Process, Neuroscience
Key=clonality, value=Polyclonal
Key=swatch_image, value=/e/k/ek0642.png
Key=rating_value, value=95.5
Key=review_count, value=4
Key=phospho_site
Key=mp_exclude_sitemap, value=No
Key=yoast_focus_keyword, value=CD68 antibody
Key=yoast_facebook_image, value=no_selection
Key=yoast_twitter_image, value=no_selection
Key=cj_related_products, value=Complement Activation:EK0966|EK0987^Fibrinolysis:EK1215^Mammary Gland Development:A00296Y1284|A06814-1
Key=description, value=Boster Bio Anti-HRG Antibody Picoband® catalog # PB9220. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-HRG Antibody Picoband® catalog # PB9220. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-HRG Antibody Picoband®
Key=contents, value=Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Key=background, value=Histidine-rich glycoprotein (HRG) is a protein that in humans is encoded by the HRG gene. It is mapped to 3q27.3. HRG contains two cystatin-like domains and is located in plasma and platelets. The protein can bind heme, dyes and divalent metal ions. It also can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. HRG is thought to have multiple roles as a protein in the human blood, including roles in immunity, angiogenesis and coagulation.
Key=gene_name, value=HRG
Key=synonyms, value=Histidine-rich glycoprotein;Histidine-proline-rich glycoprotein;HPRG;HRG;
Key=application_details, value=Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Key=subcellular_localization, value= Secreted .
Key=tissue_specificity, value= Expressed in macrophages and in malignant cells. Expressed by the liver and secreted in plasma (at protein level). .
Key=application_notes, value=WB: The detection limit for HRG is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 7892|sc 31608|sc 31609|sc 146|sc 52893|sc 65378|sc 52892|sc 146 G
Key=immunogen, value=E.coli-derived human HRG recombinant protein (Position: V19-V200). Human HRG shares 71% and 69% amino acid (aa) sequences identity with mouse and rat HRG, respectively.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=60 kDa
Key=custom_attribute_2, value=WB: Human Placenta Tissue
IHC: Human Intestinal Cancer Tissue
Key=protein_function, value= Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Binds heparin and heparin/glycosaminoglycans in a zinc-dependent manner. Binds heparan sulfate on the surface of liver, lung, kidney and heart endothelial cells. Binds to N-sulfated polysaccharide chains on the surface of liver endothelial cells. Inhibits rosette formation. Acts as an adapter protein and is implicated in regulating many processes such as immune complex and pathogen clearance, cell chemotaxis, cell adhesion, angiogenesis, coagulation and fibrinolysis. Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway. This process can be regulated by the presence of certain HRG ligands such as heparin and zinc ions. Binds to IgG subclasses of immunoglobins containing kappa and lambda light chains with different affinities regulating their clearance and inhibiting the formation of insoluble immune complexes. Tethers plasminogen to the cell surface. Binds T-cells and alters the cell morphology. Modulates angiogenesis by blocking the CD6-mediated antiangiongenic effect of thrombospondins, THBS1 and THBS2. Acts as a regulator of the vascular endothelial growth factor (VEGF) signaling pathway; inhibits endothelial cell motility by reducing VEGF-induced complex formation between PXN/paxillin and ILK/integrin-linked protein kinase and by promoting inhibition of VEGF-induced tyrosine phosphorylation of focal adhesion kinases and alpha-actinins in endothelial cells. Also plays a role in the regulation of tumor angiogenesis and tumor immune surveillance. Normalizes tumor vessels and promotes antitumor immunity by polarizing tumor-associated macrophages, leading to decreased tumor growth and metastasis. .
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