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Product Info Summary
| SKU: | A12218 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IF, IHC, WB |
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Product info
Product Name
Anti-Histone H2B HIST1H2BH Antibody
SKU/Catalog Number
A12218
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Histone H2B HIST1H2BH Antibody (Catalog # A12218). Tested in WB, IHC, IF applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Histone H2B HIST1H2BH Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12218)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human Histone H2B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A12218 is reactive to HIST1H2BH in Human
Reconstitution
Calculated molecular weight
13892 MW
Background of Hist1h2bh
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Albig W., Genomics 40:314-322(1997).
Marzluff W.F., Genomics 80:487-498(2002).
Mungall A.J., Nature 425:805-811(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12218 is guaranteed for IF, IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
Validation Images & Assay Conditions
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using Histone H2B antibody A12218.
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Western blot analysis of extracts from A549 cells, using Histone H2B antibody A12218.
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Immunofluorescence analysis of HeLa cells, using Histone H2B antibody A12218.
Protein Target Info & Infographic
Gene/Protein Information For HIST1H2BH (Source: Uniprot.org, NCBI)
Gene Name
HIST1H2BH
Full Name
Histone H2B type 1-H
Weight
13892 MW
Superfamily
histone H2B family
Alternative Names
Histone H2B type 1-H;Histone H2B.j;H2B/j;HIST1H2BH;H2BFJ;
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on HIST1H2BH, check out the HIST1H2BH Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for HIST1H2BH: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Histone H2B HIST1H2BH Antibody (A12218)
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No publications found for A12218
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