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Product Info Summary
| SKU: | A07609-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-GDF1 Antibody
SKU/Catalog Number
A07609-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-GDF1 Antibody (Catalog # A07609-1). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
GDF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-GDF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07609-1)
Host
Rabbit
Contents
GDF1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal GDF1 antibody was raised against a 16 amino acid peptide near the amino terminus of human GDF1. The immunogen is located within amino acids 30 - 80 of GDF1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
GDF1 antibody is predicted to not cross-react with any other members of the growth differentiation factor family.
Reactive Species
A07609-1 is reactive to GDF1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
39475 MW
Background of GDF-1
Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07609-1 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
GDF1 antibody can be used for detection of GDF1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of GDF1 in rat lung tissue lysate with GDF1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunofluorescence of GDF1 in human lung tissue with GDF1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For GDF1 (Source: Uniprot.org, NCBI)
Gene Name
GDF1
Full Name
Embryonic growth/differentiation factor 1
Weight
39475 MW
Superfamily
TGF-beta family
Alternative Names
RAI, DORV, DTGA3GDF-1 GDF1 CERS1, CHTD6, DORV, DTGA3, LAG1, LASS1, RAI, UOG1 growth differentiation factor 1 embryonic growth/differentiation factor 1|Ceramide synthase 1|LAG1 longevity assurance homolog 1|Longevity assurance gene 1 protein homolog 1|Protein UOG-1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GDF1, check out the GDF1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GDF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GDF1 Antibody (A07609-1)
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