Product Info Summary
SKU: | A09605 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-FREM1 Antibody
View all QBRICK/FREM1 Antibodies
SKU/Catalog Number
A09605
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-FREM1 Antibody (Catalog # A09605). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
FREM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-FREM1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09605)
Host
Rabbit
Contents
FREM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
FREM1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human FREM1. The immunogen is located within the last 50 amino acids of FREM1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
VEZT antibody is human, mouse and rat reactive. Multiple isoforms are known to exist.
Reactive Species
A09605 is reactive to FREM1 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
244154 MW
Background of QBRICK/FREM1
FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09605 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FREM1 antibody can be used for detection of FREM1 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of FREM1 in K562 cell lysate with FREM1 antibody at (A) 0.5 and (B) 1μg/mL.
Click image to see more details
Immunocytochemistry of FREM1 in K562 cells with FREM1 antibody at 20 μg/mL.
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Immunofluorescence of FREM1 in K562 cells with FREM1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For FREM1 (Source: Uniprot.org, NCBI)
Gene Name
FREM1
Full Name
FRAS1-related extracellular matrix protein 1
Weight
244154 MW
Superfamily
FRAS1 family
Alternative Names
BNAR, MOTA, TILRR, TRIGNO2, C9orf143, C9orf145, C9orf154, FRAS1-related extracellular matrix protein 1, Protein QBRICK FREM1 BNAR, C9orf143, C9orf145, C9orf154, MOTA, TILRR, TRIGNO2 FRAS1 related extracellular matrix 1 FRAS1-related extracellular matrix protein 1|extracellular matrix protein QBRICK
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FREM1, check out the FREM1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FREM1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FREM1 Antibody (A09605)
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