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Product Info Summary
| SKU: | M02562 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-FLNB Antibody (N-Term)
SKU/Catalog Number
M02562
Size
50 µl
Description
Boster Bio Anti-FLNB Antibody (N-Term) (Catalog # M02562). Tested in WB application(s). This antibody reacts with Human, Mouse.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-FLNB Antibody (N-Term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02562)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This FLNB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 288-322 amino acids from human FLNB.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M02562 is reactive to FLNB in Human, Mouse
Reconstitution
Calculated molecular weight
278164 Da
Background of Filamin B
Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M02562 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
Validation Images & Assay Conditions
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All lanes : Anti-FLNB Antibody (N-Term) at 1:2000 dilution
Lane 1: Hela whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: A431 whole cell lysate
Lane 4: 293T/17 whole cell lysate
Lane 5: NIH/3T3 whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 278 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For FLNB (Source: Uniprot.org, NCBI)
Gene Name
FLNB
Full Name
Filamin-B
Weight
278164 Da
Superfamily
filamin family
Alternative Names
Filamin-B, FLN-B, ABP-278, ABP-280 homolog, Actin-binding-like protein, Beta-filamin, Filamin homolog 1, Fh1, Filamin-3, Thyroid autoantigen, Truncated actin-binding protein, Truncated ABP, FLNB, FLN1L, FLN3, TABP, TAP FLNB ABP-278, ABP-280, AOI, FH1, FLN-B, FLN1L, LRS1, SCT, TABP, TAP filamin B filamin-B|ABP-280 homolog|Larsen syndrome 1 (autosomal dominant)|actin binding protein 278|actin-binding-like protein|beta-filamin|filamin B, beta|filamin homolog 1|filamin-3|thyroid auto
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FLNB, check out the FLNB Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FLNB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FLNB Antibody (N-Term) (M02562)
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