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Product Info Summary
| SKU: | PA1476 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Fibroblast growth factor 19 FGF19 Antibody
SKU/Catalog Number
PA1476
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Fibroblast growth factor 19 FGF19 Antibody catalog # PA1476. Tested in IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Fibroblast growth factor 19 FGF19 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1476)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human FGF19.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1476 is reactive to FGF19 in Human
Applications
PA1476 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
24 kDa
Calculated molecular weight
24003 MW
Background of FGF-19
FGF19, Fibroblast growth factor 19, is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF19 gene is mapped to 11q13.3. The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human
Validation Images & Assay Conditions
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Anti-FGF19 antibody, PA1476, Western blotting
All lanes: Anti FGF19 (PA1476) at 0.5ug/ml
Lane 1: U87 Whole Cell Lysate at 40ug
Lane 2: SMMC Whole Cell Lysate at 40ug
Predicted bind size: 24KD
Observed bind size: 24KD
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Anti-FGF19 antibody, PA1476, IHC(P)
IHC(P): Human Gallbladder Cancer Tissue
Protein Target Info & Infographic
Gene/Protein Information For FGF19 (Source: Uniprot.org, NCBI)
Gene Name
FGF19
Full Name
Fibroblast growth factor 19
Weight
24003 MW
Superfamily
heparin-binding growth factors family
Alternative Names
FGF19; FGF-19; fibroblast growth factor 19 FGF19 fibroblast growth factor 19 fibroblast growth factor 19|FGF-19
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FGF19, check out the FGF19 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FGF19: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Fibroblast growth factor 19 FGF19 Antibody (PA1476)
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