Anti-Ferritin, Light Chain (FTL) (Microglia Marker) Monoclonal Antibody

Product Name

Anti-Ferritin, Light Chain (FTL) (Microglia Marker) Monoclonal Antibody

View all Ferritin Light Chain Antibodies

SKU/Catalog Number

M01956

Size

100ug/vial

Form

Liquid

Description

Boster Bio Anti-Ferritin, Light Chain (FTL) (Microglia Marker) Monoclonal Antibody (Catalog # M01956). Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Cite This Product

Anti-Ferritin, Light Chain (FTL) (Microglia Marker) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01956)

Host

Mouse

Contents

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Clonality

Monoclonal

Clone Number

Clone: FTL/1389

Isotype

IgG1, kappa

Immunogen

Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M01956 is reactive to FTL in Human

Reconstitution

Reconstitute with distilled water.

Observed Molecular Weight

68 kDa

Calculated molecular weight

20020 MW

Background of Ferritin Light Chain

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M01956 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ELISA (For coating, order antibody without BSA)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Validation Images & Assay Conditions

Gene/Protein Information For FTL (Source: Uniprot.org, NCBI)

Alternative Names

Ferritin light chain;Ferritin L subunit;FTL; FTL LFTD, NBIA3 ferritin light chain ferritin light chain|epididymis secretory sperm binding protein|ferritin L subunit|ferritin L-chain|ferritin light polypeptide-like 3|ferritin, light polypeptide

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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