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Product Info Summary
| SKU: | M00237-1 |
|---|---|
| Size: | 100 μl |
| Reactive Species: | Mouse |
| Host: | Rabbit |
| Application: | Flow Cytometry, IHC, WB |
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Product info
Product Name
Anti-FADD Monoclonal Antibody
SKU/Catalog Number
M00237-1
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-FADD Monoclonal Antibody catalog # M00237-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-FADD Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00237-1)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
ADDE-6
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human FADD Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00237-1 is reactive to Fadd in Mouse
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Observed Molecular Weight
100-110 kDa
Calculated molecular weight
91027 MW
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00237-1 is guaranteed for Flow Cytometry, IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:50-1:200
FC 1:50
Positive Control
WB: Raw2647 cell
Validation Images & Assay Conditions
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Western blot analysis of FADD expression in Raw264.7 cell lysate.
Protein Target Info & Infographic
Gene/Protein Information For Fadd (Source: Uniprot.org, NCBI)
Gene Name
Fadd
Full Name
FAS-associated death domain protein
Weight
91027 MW
Alternative Names
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha;PGC-1-alpha;PPAR-gamma coactivator 1-alpha;PPARGC-1-alpha;Ligand effect modulator 6;PPARGC1A;LEM6, PGC1, PGC1A, PPARGC1; FADD GIG3, MORT1 Fas associated via death domain FAS-associated death domain protein|Fas (TNFRSF6)-associated via death domain|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor-induced toxicity
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Fadd, check out the Fadd Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Fadd: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FADD Monoclonal Antibody (M00237-1)
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