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Product Info Summary
| SKU: | A04269 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-ERAP2 Antibody
View all Aminopeptidase LRAP/ERAP2 Antibodies
SKU/Catalog Number
A04269
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ERAP2 Antibody (Catalog # A04269). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
ERAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-ERAP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04269)
Host
Rabbit
Contents
ERAP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. The immunogen is located within amino acids 110 - 160 of ERAP2 .
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.
Reactive Species
A04269 is reactive to ERAP2 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
110462 MW
Background of Aminopeptidase LRAP/ERAP2
The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response (reviewed in 3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04269 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ERAP2 antibody can be used for detection of ERAP2 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ERAP2 in human ovary tissue lysate with ERAP2 antibody at 1 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For ERAP2 (Source: Uniprot.org, NCBI)
Gene Name
ERAP2
Full Name
Endoplasmic reticulum aminopeptidase 2
Weight
110462 MW
Superfamily
peptidase M1 family
Alternative Names
LRAP, L-RAP, LRAP, Endoplasmic reticulum aminopeptidase 2, Leukocyte-derived arginine aminopeptidase ERAP2 L-RAP, LRAP endoplasmic reticulum aminopeptidase 2 endoplasmic reticulum aminopeptidase 2|leukocyte-derived arginine aminopeptidase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ERAP2, check out the ERAP2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ERAP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ERAP2 Antibody (A04269)
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