Anti-ERAP2 Antibody

Aminopeptidase LRAP/ERAP2 antibody

Boster Bio Anti-ERAP2 Antibody (Catalog # A04269). Tested in ELISA, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A04269
Size: 0.1 mg
Reactive Species: Human
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-ERAP2 Antibody

View all Aminopeptidase LRAP/ERAP2 Antibodies

SKU/Catalog Number

A04269

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ERAP2 Antibody (Catalog # A04269). Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

ERAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-ERAP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04269)

Host

Rabbit

Contents

ERAP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. The immunogen is located within amino acids 110 - 160 of ERAP2 .

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.

Reactive Species

A04269 is reactive to ERAP2 in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

110462 MW

Background of Aminopeptidase LRAP/ERAP2

The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response (reviewed in 3).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A04269 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ERAP2 antibody can be used for detection of ERAP2 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ERAP2 (Source: Uniprot.org, NCBI)

Gene Name

ERAP2

Full Name

Endoplasmic reticulum aminopeptidase 2

Weight

110462 MW

Superfamily

peptidase M1 family

Alternative Names

LRAP, L-RAP, LRAP, Endoplasmic reticulum aminopeptidase 2, Leukocyte-derived arginine aminopeptidase ERAP2 L-RAP, LRAP endoplasmic reticulum aminopeptidase 2 endoplasmic reticulum aminopeptidase 2|leukocyte-derived arginine aminopeptidase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ERAP2, check out the ERAP2 Infographic

ERAP2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ERAP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A04269-0.1 mg

0.1 mg

$449

Free Secondary Antibody

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A04269
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00

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