Anti-EphA6/Eph Receptor A6 Monoclonal Antibody

Product Name

Anti-EphA6/Eph Receptor A6 Monoclonal Antibody

View all Epha6 Antibodies

SKU/Catalog Number

A08818

Size

100μl

Form

Liquid

Description

Boster Bio Anti-EphA6/Eph Receptor A6 Monoclonal Antibody catalog # A08818. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-EphA6/Eph Receptor A6 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08818)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

3D5B1

Isotype

IgG

Immunogen

Purified recombinant fragment of EphA6 (aa695-795) expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A08818 is reactive to Epha6 in Human

Applications

A08818 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

116379 MW

Background of Epha6

APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214. APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G₁ phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex. APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2. APC11 shows both a cytoplasmic and nuclear localization. APC11 is expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis using EphA6 Monoclonal antibody against truncated MBP-EphA6 recombinant protein (1) and truncated GST-EphA6(aa695-795) recombinant protein (2).

Gene/Protein Information For Epha6 (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp434C1418; EC 2.7.10; EC 2.7.10.1; Ehk2; EHK-2; EPA6; EPH homology kinase 2; EPH receptor A6; EphA6; ephrin receptor EphA6; ephrin type-A receptor 6; FLJ35246; Hek12; PRO57066 Epha6|Ehk2, Hek12, m-ehk2|Eph receptor A6|ephrin type-A receptor 6|EHK-2|EPH homology kinase 2

For more info on Epha6, check out the Epha6 Infographic

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In this infographic, you will see the following information for Epha6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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