Product Info Summary
SKU: | A01351-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC |
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Product info
Product Name
Anti-eIF4G (Q1103) EIF4G1 Antibody
SKU/Catalog Number
A01351-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-eIF4G (Q1103) EIF4G1 Antibody catalog # A01351-1. Tested in IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-eIF4G (Q1103) EIF4G1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01351-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human LPPL protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01351-1 is reactive to EIF4G1 in Human, Mouse, Rat
Applications
A01351-1 is guaranteed for IF, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
175491 MW
Background of EIF4G1
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Kumagai H., Mol. Cell. Biol. 19:5083-5095(1999).
Jiang W., EMBO J. 18:5703-5713(1999).
Ota T., Nat. Genet. 36:40-45(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of EIF4G1 using Anti-eIF4G (Q1103) EIF4G1 Antibody (A01351-1).
Immunohistochemistry (IHC) analyzes of eIF4G (Q1103) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For EIF4G1 (Source: Uniprot.org, NCBI)
Gene Name
EIF4G1
Full Name
Eukaryotic translation initiation factor 4 gamma 1
Weight
175491 MW
Superfamily
eukaryotic initiation factor 4G family
Alternative Names
DKFZp686A1451; EIF4F; eIF-4G 1; eIF4G1; EIF-4G1; eIF-4-gamma 1; EIF4-gamma; EIF4GI; EIF4Gp220; eucaryotic translation initiation factor 4G; eukaryotic translation initiation factor 4 gamma 1; eukaryotic translation initiation factor 4 gamma, 1; P220 EIF4G1 EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18 eukaryotic translation initiation factor 4 gamma 1 eukaryotic translation initiation factor 4 gamma 1|EIF4-gamma|eIF-4-gamma 1|eucaryotic translation initiation factor 4G
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on EIF4G1, check out the EIF4G1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for EIF4G1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-eIF4G (Q1103) EIF4G1 Antibody (A01351-1)
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No publications found for A01351-1
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