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Product Info Summary
| SKU: | A07124 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-EFHD2 Antibody
SKU/Catalog Number
A07124
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-EFHD2 Antibody (Catalog # A07124). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
EFHD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-EFHD2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07124)
Host
Rabbit
Contents
EFHD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
EFHD2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human EFHD2. The immunogen is located within the first 50 amino acids of EFHD2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
GBP5 antibody is predicted to not cross-react with other GBP family members.
Reactive Species
A07124 is reactive to EFHD2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
26697 MW
Background of Efhd2
EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-κB-activating branch.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07124 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of EFHD2 in mouse brain tissue lysate with EFHD2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of EFHD2 in human brain tissue with EFHD2 antibody at 5 μg/mL.
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Immunofluorescence of EFHD2 in human brain tissue with EFHD2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For EFHD2 (Source: Uniprot.org, NCBI)
Gene Name
EFHD2
Full Name
EF-hand domain-containing protein D2
Weight
26697 MW
Alternative Names
SWS1, SWS1, EF-hand domain-containing protein D2, Swiprosin-1 Efhd2|2600015J22Rik, AA408606, D4Wsu27, D4Wsu27e|EF hand domain containing 2|EF-hand domain-containing protein D2|swiprosin-1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on EFHD2, check out the EFHD2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for EFHD2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-EFHD2 Antibody (A07124)
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