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Product Info Summary
| SKU: | M06431 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human, Mouse |
| Host: | Mouse |
| Application: | WB |
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Product info
Product Name
Anti-DKK2 Antibody
SKU/Catalog Number
M06431
Size
50 µl
Description
Boster Bio Anti-DKK2 Antibody (Catalog # M06431). Tested in WB application(s). This antibody reacts with Human, Mouse.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-DKK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M06431)
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1833CT856.7.20
Isotype
IgG1,k
Immunogen
This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M06431 is reactive to DKK2 in Human, Mouse
Reconstitution
Calculated molecular weight
28447 Da
Background of Dkk-2
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M06431 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
Validation Images & Assay Conditions
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All lanes : Anti-DKK2 Antibody at 1:2000 dilution
Lane 1: Human brain lysate
Lane 2: Mouse heart lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 28 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For DKK2 (Source: Uniprot.org, NCBI)
Gene Name
DKK2
Full Name
Dickkopf-related protein 2
Weight
28447 Da
Superfamily
dickkopf family
Alternative Names
Dickkopf-related protein 2, Dickkopf-2, Dkk-2, hDkk-2, DKK2 DKK2 DKK-2 dickkopf WNT signaling pathway inhibitor 2 dickkopf-related protein 2|dickkopf 2 homolog|dickkopf homolog 2|dickkopf-2|hDkk-2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DKK2, check out the DKK2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DKK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DKK2 Antibody (M06431)
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No publications found for M06431
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