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Product Info Summary
| SKU: | A05407 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-DDX41 Antibody
SKU/Catalog Number
A05407
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DDX41 Antibody (Catalog # A05407). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
DDX41 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-DDX41 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05407)
Host
Rabbit
Contents
DDX41 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41. The immunogen is located within amino acids 230 - 280 of DDX41.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of DDX41 are known to exist; this antibody will detect both isoforms.
Reactive Species
A05407 is reactive to DDX41 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
69838 MW
Background of DDX41
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05407 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of DDX41 in rat brain tissue lysate with DDX41 antibody at 1 μg/mL.
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Immunohistochemistry of DDX41 in rat brain tissue with DDX41 antibody at 2.5 μg/ml.
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Immunofluorescence of DDX41 in rat brain tissue with DDX41 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For DDX41 (Source: Uniprot.org, NCBI)
Gene Name
DDX41
Full Name
Probable ATP-dependent RNA helicase DDX41
Weight
69838 MW
Superfamily
DEAD box helicase family
Alternative Names
ABS, ABS, Probable ATP-dependent RNA helicase DDX41, DEAD box protein 41 DDX41 ABS, MPLPF DEAD-box helicase 41 probable ATP-dependent RNA helicase DDX41|DEAD (Asp-Glu-Ala-Asp) box polypeptide 41|DEAD box protein 41|DEAD box protein abstrakt homolog|DEAD-box protein abstrakt|putative RNA helicase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DDX41, check out the DDX41 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DDX41: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DDX41 Antibody (A05407)
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