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Product Info Summary
| SKU: | M09701 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry, WB |
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Product info
Product Name
Anti-DDIT4L Purified Monoclonal Antibody
SKU/Catalog Number
M09701
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DDIT4L Purified Monoclonal Antibody (Catalog# M09701). Tested in Flow Cytometry, WB application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-DDIT4L Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M09701)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
DDIT-03
Isotype
Mouse IgG1
Immunogen
N-terminal recombinant fragment of human DDIT4L (amino acids 2-98). The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
As in case with other anti-CD170 antibodies, this antibody cross-reacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.
Reactive Species
M09701 is reactive to DDIT4L in Human
Reconstitution
Observed Molecular Weight
42 kDa
Calculated molecular weight
21740 MW
Background of Ddit4l
DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M09701 is guaranteed for Flow Cytometry, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml. Intracellular staining.
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For DDIT4L (Source: Uniprot.org, NCBI)
Gene Name
DDIT4L
Full Name
DNA damage-inducible transcript 4-like protein
Weight
21740 MW
Superfamily
DDIT4 family
Alternative Names
DDIT4L, REDD2, Rtp801L Ddit4l|1700037B15Rik, 1700108M02Rik, REDD, REDD2, RTP8, RTP801L, Smhs1|DNA-damage-inducible transcript 4-like|DNA damage-inducible transcript 4-like protein|HIF-1 responsive protein RTP801-like|skeletal muscle hindlimb suspension 1|soleus muscle atrophied after hindlimb suspension protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DDIT4L, check out the DDIT4L Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DDIT4L: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DDIT4L Purified Monoclonal Antibody (M09701)
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No publications found for M09701
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