Anti-Cytochrome P450 3A7 CYP3A7 Antibody

Product Name

Anti-Cytochrome P450 3A7 CYP3A7 Antibody

View all CYP3A7 Antibodies

SKU/Catalog Number

A05417

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Cytochrome P450 3A7 CYP3A7 Antibody (Catalog # A05417). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Cytochrome P450 3A7 CYP3A7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05417)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human Cytochrome P450 3A7.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05417 is reactive to CYP3A7 in Human

Reconstitution

Observed Molecular Weight

111 kDa

Calculated molecular weight

57526 MW

Background of CYP3A7

This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3AP1 pseudogene and is represented by GeneID:100861540.

Komori M., J. Biochem. 105:161-163(1989).
Gellner K., Pharmacogenetics 11:111-121(2001).
Scherer S.W., Science 300:767-772(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A05417 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For CYP3A7 (Source: Uniprot.org, NCBI)

Alternative Names

Cytochrome P450 3A7;1.14.14.1;CYPIIIA7;Cytochrome P450-HFLA;CYP3A7; CYP3A7 CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA, P450HLp2 cytochrome P450 family 3 subfamily A member 7 cytochrome P450 3A7|aryl hydrocarbon hydroxylase|cytochrome P450, family 3, subfamily A, polypeptide 7|cytochrome P450, subfamily IIIA, polypeptide 7|cytochrome P450-HFLA|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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