Click image to see more details
Product Info Summary
| SKU: | A12025 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Mouse |
| Application: | WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-COBRA1 (NELF B) Antibody
SKU/Catalog Number
A12025
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-COBRA1 (NELF B) Antibody (Catalog # A12025). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year. After date of receipt, stable for at least 1 year at -20°C.
Cite This Product
Anti-COBRA1 (NELF B) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12025)
Host
Mouse
Contents
PBS + 0.05% NaN3
Clonality
Monoclonal
Clone Number
F7E4
Isotype
IgG1
Immunogen
Recombinant full length human COBRA1 purified from E. coli. Immunogen species is Human.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A12025 is reactive to COBRA1 in Human, Mouse, Rat
Reconstitution
Calculated molecular weight
65697 MW
Background of NELFB
COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12025 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
Validation Images & Assay Conditions
Click image to see more details
Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~62 kDa COBRA1 protein.
Protein Target Info & Infographic
Gene/Protein Information For COBRA1 (Source: Uniprot.org, NCBI)
Gene Name
COBRA1
Full Name
Negative elongation factor B
Weight
65697 MW
Superfamily
NELF-B family
Alternative Names
A730008L03Rik antibody, AB041607 antibody, AI663983 antibody, Cofactor of BRCA1 antibody, DKFZp586B0519 antibody, KIAA1182 antibody, Negative elongation factor B antibody, Negative elongation factor protein B antibody, Nelf b antibody, NELF-B antibody, NELFB antibody, RGD1307832 antibody, RP13-122B23.3 antibody, RP23-132N23.4 antibody NELFB COBRA1, NELF-B negative elongation factor complex member B negative elongation factor B|cofactor of BRCA1|negative elongation factor protein B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on COBRA1, check out the COBRA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for COBRA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-COBRA1 (NELF B) Antibody (A12025)
Hello CJ!
No publications found for A12025
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-COBRA1 (NELF B) Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-COBRA1 (NELF B) Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
