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Product Info Summary
| SKU: | A10988 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-CDIP CDIP1 Antibody
SKU/Catalog Number
A10988
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CDIP CDIP1 Antibody (Catalog # A10988). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
CDIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CDIP CDIP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10988)
Host
Rabbit
Contents
CDIP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CDIP antibody was raised against a 16 amino acid synthetic peptide near the center of human CDIP. The immunogen is located within amino acids 40 - 90 of CDIP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of MTERFD1 are known to exist. MTERFD1 antibody is predicted to not cross-react with other MTERFD protein family members.
Reactive Species
A10988 is reactive to CDIP1 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
21892 MW
Background of CDIP
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A10988 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CDIP antibody can be used for detection of CDIP by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CDIP in human brain lysate with CDIP antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of FNIP2 in mouse brain tissue with FNIP2 antibody at 2.5 μg/mL.
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Immunofluorescence of CDIP1 in mouse brain tissue with CDIP1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CDIP1 (Source: Uniprot.org, NCBI)
Gene Name
CDIP1
Full Name
Cell death-inducing p53-target protein 1
Weight
21892 MW
Superfamily
CDIP1/LITAF family
Alternative Names
I1, CDIP, LITAFL, C16orf5, Cell death-inducing p53-target protein 1, Cell death involved p53-target CDIP1 C16orf5, CDIP, I1, LITAFL cell death inducing p53 target 1 cell death-inducing p53-target protein 1|LITAF-like protein|cell death inducing protein|cell death involved p53-target|lipopolysaccharide-induced tumor necrosis factor-alpha-like protein|transmembrane protein I1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CDIP1, check out the CDIP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CDIP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CDIP CDIP1 Antibody (A10988)
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No publications found for A10988
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