Anti-CCR6/CCR6 Antibody Picoband®

Product Name

Anti-CCR6/CCR6 Antibody Picoband®

View all CCR6 Antibodies

SKU/Catalog Number

PA1201

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CCR6/CCR6 Antibody catalog # PA1201. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CCR6/CCR6 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1201)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6, different from the related rat and mouse sequences by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1201 is reactive to CCR6 in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

120 kDa

Calculated molecular weight

42494 MW

Background of CCR6

CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca (2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1201 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Positive Control

WB: Rat Liver Tissue, SW620 Cell, CEM Cell

Validation Images & Assay Conditions

Gene/Protein Information For CCR6 (Source: Uniprot.org, NCBI)

Alternative Names

C-C chemokine receptor type 6;C-C CKR-6;CC-CKR-6;CCR-6;Chemokine receptor-like 3;CKR-L3;DRY6;G-protein coupled receptor 29;GPR-CY4;GPRCY4;LARC receptor;CD196;CCR6;CKRL3, CMKBR6, GPR29, STRL22; CCR6 BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22 C-C motif chemokine receptor 6 C-C chemokine receptor type 6|G protein-coupled receptor 29|LARC receptor|chemokine (C-C motif) receptor 6|chemokine (C-C) receptor 6|chemokine receptor-like 3|seven-transmembrane receptor, lymphocyte, 22

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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