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Key=updated_at, value=2024-09-26 00:46:26
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Key=name, value=Anti-Caspase-7/CASP7 Antibody Picoband®
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Key=price, value=370.0000
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Key=meta_title, value=Caspase-7/CASP7 Antibody
Key=meta_description, value=Boster Bio Anti-Caspase-7/CASP7 Antibody Picoband® catalog # PB9369. Tested in IHC, WB applications. This antibody reacts with Human, Rat. Supplied as 100μg/vial in Lyophilized form antibody.
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Key=image_label, value=Anti- Caspase-7 Picoband antibody, PB9369, Western blotting
All lanes: Anti Caspase-7(PB9369) at 0.5ug/ml
Lane 1: A549 Whole Cell Lysate at 40ug
Lane 2: Rat Spleen Tissue Lysate at 50ug
Lane 3: Rat Lung Tissue Lysate at 50ug
Predicted bind
Key=small_image_label, value=Anti- Caspase-7 Picoband antibody, PB9369, Western blotting
All lanes: Anti Caspase-7(PB9369) at 0.5ug/ml
Lane 1: A549 Whole Cell Lysate at 40ug
Lane 2: Rat Spleen Tissue Lysate at 50ug
Lane 3: Rat Lung Tissue Lysate at 50ug
Predicted bind
Key=thumbnail_label, value=Anti- Caspase-7 Picoband antibody, PB9369, Western blotting
All lanes: Anti Caspase-7(PB9369) at 0.5ug/ml
Lane 1: A549 Whole Cell Lysate at 40ug
Lane 2: Rat Spleen Tissue Lysate at 50ug
Lane 3: Rat Lung Tissue Lysate at 50ug
Predicted bind
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Key=size, value=100 μg/vial
Key=protein_name, value=Caspase-7
Key=gene_full_name, value=Caspase-7
Key=uniprot_id, value=P55210
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=IHC, WB
Key=reactivity, value=Human, Rat
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Key=predicted_reactivity
Key=source_company, value=Boster PB9369
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=34277 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Apoptosis, Apoptotic Markers, Cancer, Caspases, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes
Key=clonality, value=Polyclonal
Key=swatch_image, value=/e/k/ek0770_2.png
Key=rating_value, value=100
Key=review_count, value=3
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Key=yoast_focus_keyword, value=CD68 antibody
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Key=cj_related_products, value=Apoptotic Dna Fragmentation:PA1442|A01044-2^Caspases:A02384-1^Execution Phase Of Apoptosis:A01044-2^Ubiquitin Proteasome Pathway:A06639-1
Key=description, value=Boster Bio Anti-Caspase-7/CASP7 Antibody Picoband® catalog # PB9369. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-Caspase-7/CASP7 Antibody Picoband® catalog # PB9369. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-Caspase-7/CASP7 Antibody Picoband®
Key=contents, value=Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Key=background, value=CASP7, Caspase-7, apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta (PRKCD)-dependent pathway.
Key=gene_name, value=CASP7
Key=synonyms, value=Caspase-7;CASP-7;3.4.22.60;Apoptotic protease Mch-3;CMH-1;ICE-like apoptotic protease 3;ICE-LAP3;Caspase-7 subunit p20;Caspase-7 subunit p11;CASP7;MCH3;
Key=application_details, value=Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat

Key=subcellular_localization, value= Cytoplasm.
Key=sequence_similarities, value=Belongs to the peptidase C14A family.
Key=tissue_specificity, value= Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Key=protein_function, value= Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death.
Key=application_notes, value=WB: The detection limit for Caspase-7 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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Key=immunogen, value=E.coli-derived human CASP7 recombinant protein (Position: A117-D198). Human CASP7 shares 92.7% amino acid (aa) sequence identity with both mouse and rat CASP7.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=34 kDa
Key=custom_attribute_2, value=WB: A549 Whole Cell, Rat Spleen Tissue, Rat Lung Tissue
IHC: Human Mammary Cancer Tissue
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Anti-Caspase-7/CASP7 Antibody Picoband®

Caspase-7 antibody

Boster Bio Anti-Caspase-7/CASP7 Antibody Picoband® catalog # PB9369. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. Cited in 2 publication(s).

Product Info Summary

SKU: PB9369
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-Caspase-7/CASP7 Antibody Picoband®

View all Caspase-7 Antibodies

SKU/Catalog Number

PB9369

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Caspase-7/CASP7 Antibody Picoband® catalog # PB9369. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Caspase-7/CASP7 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9369)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human CASP7 recombinant protein (Position: A117-D198). Human CASP7 shares 92.7% amino acid (aa) sequence identity with both mouse and rat CASP7.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9369 is reactive to CASP7 in Human, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

34 kDa

Calculated molecular weight

34277 MW

Background of Caspase-7

CASP7, Caspase-7, apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta (PRKCD)-dependent pathway.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

PB9369 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat

Positive Control

WB: A549 Whole Cell, Rat Spleen Tissue, Rat Lung Tissue
IHC: Human Mammary Cancer Tissue

Validation Images & Assay Conditions

Gene/Protein Information For CASP7 (Source: Uniprot.org, NCBI)

Gene Name

CASP7

Full Name

Caspase-7

Weight

34277 MW

Superfamily

peptidase C14A family

Alternative Names

Caspase-7;CASP-7;3.4.22.60;Apoptotic protease Mch-3;CMH-1;ICE-like apoptotic protease 3;ICE-LAP3;Caspase-7 subunit p20;Caspase-7 subunit p11;CASP7;MCH3; CASP7 CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7 caspase-7|ICE-like apoptotic protease 3|apoptotic protease MCH-3|caspase 7, apoptosis-related cysteine peptidase|caspase 7, apoptosis-related cysteine protease

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CASP7, check out the CASP7 Infographic

CASP7 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CASP7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9369 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL%u20101%u03B2/NF%u2010%u03BAB pathway

Rasul A, Yu B, Khan M, Zhang K, Iqbal F, Ma T, Yang H. Int J Oncol. 2012 Apr;40(4):1153-61. Doi: 10.3892/Ijo.2011.1277. Epub 2011 Nov 30. Magnolol, A Natural Compound, Induces Apoptosis Of Sgc-7901 Human Gastric Adenocarcinoma Cells Vi...

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1 Customer Q&As for Anti-Caspase-7/CASP7 Antibody Picoband®

Question

We are currently using anti-Caspase-7/CASP7 antibody PB9369 for human tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, rat. Is it likely that the antibody can work on canine tissues as well?

D. Yang

Verified customer

Asked: 2013-10-30

Answer

The anti-Caspase-7/CASP7 antibody (PB9369) has not been validated for cross reactivity specifically with canine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2013-10-30

Order DetailsPrice
PB9369

100μg

$370
PB9369-10ug

10μg sample (liquid)

$99
PB9369-Biotin

100 μg Biotin conjugated

$570
PB9369-Cy3

100 μg Cy3 conjugated

$570
PB9369-Dylight488

100 μg Dylight488 conjugated

$570
PB9369-Dylight550

100 μg Dylight550 conjugated

$570
PB9369-Dylight594

100 μg Dylight594 conjugated

$570
PB9369-FITC

100 μg FITC conjugated

$570
PB9369-HRP

100 μg HRP conjugated

$570
PB9369-APC

100 μg APC conjugated

$670
PB9369-PE

100 μg PE conjugated

$670
PB9369-iFluor647

100 μg iFluor647 conjugated

$670
PB9369-carrier-free

Carrier Free

$370

More conjugates/formats

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PB9369
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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