Anti-Cadherin-18 Antibody

Product Name

Anti-Cadherin-18 Antibody

View all Cadherin-18 Antibodies

SKU/Catalog Number

A12825

Size

100μl

Form

Liquid

Description

Boster Bio Anti-Cadherin-18 Antibody catalog # A12825. Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Cadherin-18 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12825)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Cadherin-18. at AA rangle: 70-150

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12825 is reactive to CDH18 in Human, Mouse

Applications

A12825 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

88073 MW

Background of Cadherin-18

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using Cadherin-18 Polyclonal antibody.

Gene/Protein Information For CDH18 (Source: Uniprot.org, NCBI)

Alternative Names

cadherin 18, type 2; cadherin-14; cadherin-18; cadherin-like 24; CDH14EY-CADHERIN; CDH14L; CDH24; ey-cadherin CDH18 CDH14, CDH14L, CDH24 cadherin 18 cadherin-18|cadherin 18, type 2|cadherin-14|cadherin-like 24|ey-cadherin

For more info on CDH18, check out the CDH18 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CDH18: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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