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Key=updated_at, value=2024-10-27 05:01:49
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Key=meta_description, value=Boster Bio Anti-Bradykinin Receptor B2 Antibody catalog # A03117. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.
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Key=image_label, value=Figure 1. Western blot analysis of Bdkrb2 using anti-Bdkrb2 antibody (A03117).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample
Key=small_image_label, value=Figure 1. Western blot analysis of Bdkrb2 using anti-Bdkrb2 antibody (A03117).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample
Key=thumbnail_label, value=Figure 1. Western blot analysis of Bdkrb2 using anti-Bdkrb2 antibody (A03117).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample
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Key=protein_name, value=AT-rich interactive domain-containing protein 5B
Key=gene_full_name, value=AT-rich interactive domain-containing protein 5B
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Key=applications, value=ELISA, IHC, WB
Key=reactivity, value=Mouse, Rat
Key=form, value=Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.
Key=concentration, value=0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Key=cross_reactivity, value=No cross reactivity with other proteins.
Key=predicted_reactivity, value=Chimpanzee
Key=source_company, value=Enzo ADI-905-747-100, Cost: 320.25
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=132375 MW
Key=sample_size_available, value=25ug for $99, contact us for details
Key=related_product_skus, value=M02870
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cardiovascular, Vasculature
Key=clonality, value=Polyclonal
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Key=cj_related_products, value=Cardiac Complication:M06063-2|M06063-1^Hyperalgesia:A00341|A00341-1^Panic Disorder:PB10047|M03117
Key=description, value=Boster Bio Anti-Bradykinin Receptor B2 Antibody catalog # A03117. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.
Key=short_description, value=Boster Bio Anti-Bradykinin Receptor B2 Antibody catalog # A03117. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.
Key=meta_keyword, value=Anti-MRF2 ARID5B Antibody
Key=contents, value=Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.
Key=background, value=FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is ubiquitously expressed. Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.
Key=gene_name, value=Bdkrb2
Key=synonyms, value=AT-rich interactive domain-containing protein 5B;ARID domain-containing protein 5B;MRF1-like protein;Modulator recognition factor 2;MRF-2;ARID5B;DESRT, MRF2;
Key=application_details, value=Optimal conditions must be determined individually for each application.
Key=subcellular_localization, value= Nucleus.
Key=tissue_specificity, value= Widely expressed, including in liver (at protein level).
Key=protein_function, value= Transcription coactivator that binds to the 5'-AATA[CT]- 3' core sequence and plays a key role in adipogenesis and liver development. Acts by forming a complex with phosphorylated PHF2, which mediates demethylation at Lys-336, leading to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2- ARID5B complex acts as a coactivator of HNF4A in liver. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes. Overexpression leads to induction of smooth muscle marker genes, suggesting that it may also act as a regulator of smooth muscle cell differentiation and proliferation. Represses the cytomegalovirus enhancer. .
Key=application_notes, value=This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 63 kDa in size corresponding to FANCC by western blotting in the appropriate human tissue.
Key=competitor_equivalent_skus, value=sc 163093
Key=immunogen, value=Synthetic peptide corresponding to the sequence near the N-terminus of rat bradykinin receptor B2.
Key=purification, value=Peptide affinity purified.
Key=storage, value=Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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Anti-Bradykinin Receptor B2 Antibody

Bradykinin RB2/BDKRB2 antibody

Boster Bio Anti-Bradykinin Receptor B2 Antibody catalog # A03117. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Product Info Summary

SKU: A03117
Size: 100µg
Reactive Species: Mouse, Rat
Host: Rabbit
Application: ELISA, IHC, WB

Product Name

Anti-Bradykinin Receptor B2 Antibody

View all Bradykinin RB2/BDKRB2 Antibodies

SKU/Catalog Number

A03117

Size

100µg

Form

Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.

Description

Boster Bio Anti-Bradykinin Receptor B2 Antibody catalog # A03117. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Bradykinin Receptor B2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03117)

Host

Rabbit

Contents

Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to the sequence near the N-terminus of rat bradykinin receptor B2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03117 is reactive to Bdkrb2 in Mouse, Rat

Reconstitution

Calculated molecular weight

132375 MW

Background of Bradykinin RB2/BDKRB2

FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is ubiquitously expressed. Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A03117 is guaranteed for ELISA, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Optimal conditions must be determined individually for each application.

Validation Images & Assay Conditions

Gene/Protein Information For Bdkrb2 (Source: Uniprot.org, NCBI)

Gene Name

Bdkrb2

Full Name

B2 bradykinin receptor

Weight

132375 MW

Superfamily

G-protein coupled receptor 1 family

Alternative Names

AT-rich interactive domain-containing protein 5B;ARID domain-containing protein 5B;MRF1-like protein;Modulator recognition factor 2;MRF-2;ARID5B;DESRT, MRF2; BDKRB2 B2R, BK-2, BK2, BKR2, BRB2 bradykinin receptor B2 B2 bradykinin receptor|BK-2 receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Bdkrb2, check out the Bdkrb2 Infographic

Bdkrb2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Bdkrb2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A03117-100ug

100 μg

$577

Free Secondary Antibody

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A03117
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$577.00

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