Anti-beta Defensin 1/DEFB1 Antibody Picoband®

Product Name

Anti-beta Defensin 1/DEFB1 Antibody Picoband®

View all DEFB1 Antibodies

SKU/Catalog Number

PA1450

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-beta Defensin 1/DEFB1 Antibody catalog # PA1450. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-beta Defensin 1/DEFB1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1450)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1450 is reactive to DEFB1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

7 kDa

Calculated molecular weight

7420 MW

Background of DEFB1

DEFB1,Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1450 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: COLO320 Whole Cell
IHC: Lung Cancer Tissue

Validation Images & Assay Conditions

Gene/Protein Information For DEFB1 (Source: Uniprot.org, NCBI)

Alternative Names

Beta-defensin 1;BD-1;hBD-1;Defensin, beta 1;DEFB1;BD1, HBD1; DEFB1 BD1, DEFB-101, HBD1, DEFB1 defensin beta 1 beta-defensin 1|BD-1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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