Anti-Bcl-2-like protein 12 BCL2L12 Antibody

Product Name

Anti-Bcl-2-like protein 12 BCL2L12 Antibody

View all BCL2L12 Antibodies

SKU/Catalog Number

A06508

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Bcl-2-like protein 12 BCL2L12 Antibody (Catalog # A06508). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Bcl-2-like protein 12 BCL2L12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06508)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human BCL2L12.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A06508 is reactive to BCL2L12 in Human

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Calculated molecular weight

36821 MW

Background of BCL2L12

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].
Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].
Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A06508 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For BCL2L12 (Source: Uniprot.org, NCBI)

Alternative Names

Bcl-2-like protein 12;Bcl2-L-12;Bcl-2-related proline-rich protein;BCL2L12;BPR; BCL2L12 BCL2 like 12 bcl-2-like protein 12|BCL2-like 12 (proline rich)|Bcl-2 related proline-rich protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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