Key=store_id Key=entity_id, value=76070 Key=attribute_set_id, value=4 Key=type_id, value=simple Key=sku, value=A13963-1 Key=has_options, value=1 Key=required_options, value=1 Key=created_at, value=2020-03-11 06:18:49 Key=updated_at, value=2024-09-26 01:03:16 Key=mst_search_weight, value=0 Key=status, value=Enabled Key=name, value=Anti-BCAS4 Antibody Key=cj_search_index Key=publication_count, value=0 Key=qty_in_warehouses Key=is_recurring, value=No Key=visibility, value=Catalog, Search Key=tax_class_id, value=Taxable Goods Key=conjugate Key=featured, value=No Key=featured_image, value=Yes Key=fb_product, value= Key=custom_product_page, value=No Key=free_shipping, value=No Key=template, value=antibodies Key=host, value=Rabbit Key=quantity_and_stock_status Key=googleshopping_exclude, value=No Key=yoast_keyword_score, value=-1371 Key=yoast_content_score, value=60 Key=price, value=449.0000 Key=weight, value=1.0000 Key=meta_title, value=Anti-BCAS4 Antibody A13963-1 Key=meta_description, value=Boster Bio Anti-BCAS4 Antibody (Catalog # A13963-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse. Supplied as 0.1 mg in Liquid form antibody. Key=image, value=no_selection Key=small_image, value=no_selection Key=thumbnail, value=no_selection Key=url_key, value=anti-bcas4-antibody-a13963-1-boster Key=url_path, value=anti-il-8-antibody-a00423-boster Key=options_container, value=Block after Info Column Key=msrp_display_actual_price_type, value=Use config Key=gift_message_available, value=No Key=size, value=0.1 mg Key=protein_name, value=Breast carcinoma amplified sequence 4 Key=gene_full_name, value=Breast carcinoma amplified sequence 4 Key=uniprot_id, value=Q8TDM0 Key=sensitivity Key=applications, value=ELISA, IF, IHC-P, WB Key=reactivity, value=Human, Mouse Key=form, value=Liquid Key=concentration, value=1 mg/mL Key=cross_reactivity, value=TCTEX1D3 is predicted to not cross-react with other members of the TCTEX-type family Key=clone_number Key=predicted_reactivity, value=Mouse Key=source_company, value=Prosci 5631; Cost: 249 Key=isotype, value=IgG Key=molecular_weight, value=22758 MW Key=sample_size_available, value=25ug for $99, contact us for details Key=related_product_skus, value=EK0413,PB9621,PROTP10145,PROTP10145-1,PROTP10145-2,PROTP10145-3,PROTP19874,PROTP26894,PROTP41324,PROTP67813 Key=product_category, value=Primary Antibodies Key=research_category, value=Cancer, Cell Cycle Key=clonality, value=Polyclonal Key=swatch_image, value=no_selection Key=rating_value, value=100 Key=review_count, value=4 Key=mp_exclude_sitemap, value=No Key=yoast_facebook_image, value=no_selection Key=yoast_twitter_image, value=no_selection Key=cj_related_products, value=Charge Syndrome:A06129|A04079^Duane Retraction Syndrome:EK1861|M06401|A08328^Fallopian Tube Neoplasms:A12841 Key=description, value=Boster Bio Anti-BCAS4 Antibody (Catalog # A13963-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse. Key=short_description, value=Boster Bio Anti-BCAS4 Antibody (Catalog # A13963-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse. Key=meta_keyword, value=Anti-BCAS4 Antibody Key=contents, value=BCAS4 Antibody is supplied in PBS containing 0.02% sodium azide. Key=background, value=The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by the cloning of a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is only found in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines. The role of BCAS4 is unknown but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting BCAS4 plays other roles in multiple tissues. Key=gene_name, value=BCAS4 Key=synonyms, value=CNOL, Breast carcinoma-amplified sequence 4 Key=application_details, value=BCAS4 antibody can be used for detection of BCAS4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher. Key=subcellular_localization, value=Cytoplasm .
Key=tissue_specificity, value=Brain, thymus, spleen, kidney and placenta.
Overexpressed in most breast cancer cell lines.
Key=protein_function, value=May be an accessory component of axonemal dynein and
cytoplasmic dynein 1. Candidate for involvement in male sterility
(By similarity). .
Key=application_notes Key=description_before_attributes Key=competitor_equivalent_skus, value=sc 25342|sc 55462|sc 7165|sc 4600|sc 73321|sc 7922|sc 1269|sc 376750|sc 8427|sc 7302|sc 52870|sc 101499|sc 32817|sc 71367 Key=immunogen, value=BCAS4 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human BCAS4. The immunogen is located within the first 50 amino acids of BCAS4. Key=purification, value=BCAS4 Antibody is affinity chromatography purified via peptide column. Key=storage, value=BCAS4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures. Key=custom_attribute_1, value=68 kDa Key=options Key=media_gallery Key=extension_attributes Key=tier_price Key=tier_price_changed Key=category_ids Key=is_salable Key=website_ids Key=request_path Key=rating_summary Key=_cache_instance_store_filter Key=media_gallery_images
Anti-BCAS4 Antibody
BASC4 antibody
Boster Bio Anti-BCAS4 Antibody (Catalog # A13963-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Boster Bio Anti-BCAS4 Antibody (Catalog # A13963-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
BCAS4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-BCAS4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13963-1)
Host
Rabbit
Contents
BCAS4 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
BCAS4 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human BCAS4. The immunogen is located within the first 50 amino acids of BCAS4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TCTEX1D3 is predicted to not cross-react with other members of the TCTEX-type family
Reactive Species
A13963-1 is reactive to BCAS4 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
22758 MW
Background of BASC4
The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by the cloning of a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is only found in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines. The role of BCAS4 is unknown but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting BCAS4 plays other roles in multiple tissues.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
BCAS4 antibody can be used for detection of BCAS4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of BCAS4 in 3T3 cell lysate with BCAS4 antibody at (A) 1 and (B) 2 μg/mL.
Click image to see more details
Immunohistochemistry of BCAS4 in human breast carcinoma with BCAS4 antibody at 5 μg/mL.
Click image to see more details
Immunofluorescence of BCAS4 in human breast carcinoma tissue with BCAS4 antibody at 20 μg/mL.
Gene/Protein Information For BCAS4 (Source: Uniprot.org, NCBI)
Gene Name
BCAS4
Full Name
Breast carcinoma-amplified sequence 4
Weight
22758 MW
Superfamily
cappuccino family
Alternative Names
CNOL, Breast carcinoma-amplified sequence 4 BCAS4 CNOL breast carcinoma amplified sequence 4 breast carcinoma-amplified sequence 4|BCAS4/BCAS3 fusion|breast carcinoma amplified sequence 4/3 fusion protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on BCAS4, check out the BCAS4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BCAS4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00
Troubleshooting
Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.