Product Info Summary
SKU: | A04089 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-BATF Antibody
SKU/Catalog Number
A04089
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-BATF Antibody (Catalog # A04089). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
BATF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-BATF Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04089)
Host
Rabbit
Contents
BATF Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
BATF antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BATF. The immunogen is located within the first 50 amino acids of BATF.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of BATF are known to exist. Despite its predicted molecular weight, BATF often migrates at a higher than expected molecular weight.
Reactive Species
A04089 is reactive to BATF in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
14120 MW
Background of BATF
BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04089 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
BATF antibody can be used for detection of BATF by Western blot at 0.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of BATF in rat spleen tissue lysate with BATF antibody at 1 μg/mL.
Click image to see more details
Immunofluorescence of BATF in human spleen tissue with BATF antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For BATF (Source: Uniprot.org, NCBI)
Gene Name
BATF
Full Name
Basic leucine zipper transcriptional factor ATF-like
Weight
14120 MW
Superfamily
bZIP family
Alternative Names
SFA2, B-ATF, BATF1, SFA-2, Basic leucine zipper transcriptional factor ATF-like, B-cell-activating transcription factor BATF B-ATF1, SFA-2, SFA2, BATF basic leucine zipper ATF-like transcription factor basic leucine zipper transcriptional factor ATF-like|B-cell-activating transcription factor|SF-HT-activated gene 2 protein|activating transcription factor B|basic leucine zipper transcription factor, ATF-like
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BATF, check out the BATF Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BATF: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-BATF Antibody (A04089)
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