Anti-Aquaporin 0/MIP Antibody Picoband®

Product Name

Anti-Aquaporin 0/MIP Antibody Picoband®

View all Aquaporin-0 Antibodies

SKU/Catalog Number

PA2110

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Aquaporin 0/MIP Antibody catalog # PA2110. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Aquaporin 0/MIP Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2110)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 0, identical to the related rat sequence, and different from the related human sequence by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2110 is reactive to Mip in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

50 kDa

Calculated molecular weight

27891 MW

Background of Aquaporin-0

Lens fiber major intrinsic protein also called MIP26 or MP26 is a protein that in humans is encoded by the MIP gene. MIP is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. Using 2-color fluorescence in situ hybridization on high-resolution R-banded chromosomes and human genomic DNA clones for MIP as probes, this gene was found that located in close proximity in region 12q13. MIP plays a crucial role in the development of a transparent eye lens. This gene may be responsible for regulating the osmolarity of the lens and interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2110 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Mouse, Human, Rat

Positive Control

WB: Mouse Spleen Tissue, Mouse Intestine Tissue

Validation Images & Assay Conditions

Gene/Protein Information For Mip (Source: Uniprot.org, NCBI)

Alternative Names

Lens fiber major intrinsic protein;Aquaporin-0;MIP26;MP26;Mip; MIP AQP0, CTRCT15, LIM126, MP26, MIP major intrinsic protein of lens fiber lens fiber major intrinsic protein|aquaporin 0

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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