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MIP Antibodies
AND MIP ELISA kits, MIP Proteins
Many biological assays use antibodies to detect MIP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MIP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MIP antibodies...
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MIP Infographic by Boster Bio
All MIP Products
Product
Figures
Specificity
Applications
Price
Anti-Aquaporin 0/MIP Antibody Picoband®
5 Citations 1 Q&As
Human, Rat
WB
$370
Cat # PB9811
100 μg/vial
Cat # PB9811
100 μg/vial
Anti-Aquaporin 0/MIP Antibody Picoband®
5 Citations 6 Q&As
Human, Mouse, Rat
WB
$370
Cat # PA2110
100 μg/vial
Cat # PA2110
100 μg/vial
MIP Overview
Facts about Lens fiber major intrinsic protein.
Lens fiber major intrinsic protein (MIP)
Water channel (PubMed:24120416). Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased.
May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes can stabilize cell junctions in the eye lens center (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | MIP |
| Uniprot: | P30301 |
| Entrez: | 4284 |
Family
| Belongs to: |
|---|
| MIP/aquaporin (TC 1.A.8) family |
Alternative Names
aquaporin 0; lens fiber major intrinsic protein; major intrinsic protein of lens fiber; MP26
Molecular Weight
Mass (kDA):
28.122 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.3 |
| Sequence: | 12; NC_000012.12 (56449502..56456553, complement) |
Tissue Specificity
Major component of lens fiber gap junctions.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Diseases
- Inflammation
- Stenosis
- Neoplasms
- Malignant Neoplasms
- Cholangiocarcinoma
- Lung Diseases
- Pneumonia
- Hiv Infections
- Aneurysm
- Chronic Obstructive Airway Disease
- Lung Diseases, Obstructive
- Hyperparathyroidism, Primary
Pathways
- Secretion
- Localization
- Pathogenesis
- Inflammatory Response
- Chemotaxis
- Immune Response
- Transport
- Chemokine Production
- Cytokine Production
- Virulence
- Cell Adhesion
- Cell Proliferation
- Aging
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Oxidation
- Acetylation
- Reduction
- Iodination
- Biotinylation
- Glycosylation
- Dephosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MIP
bosterbio.com/bosterbio-gene-info-cards/MIP
References
PMID: 1840563 by Pisano M.M., et al. Genomic cloning, complete nucleotide sequence, and structure of the human gene encoding the major intrinsic protein (MIP) of the lens.
PMID: 10634618 by Schey K.L., et al. Characterization of human lens major intrinsic protein structure.
5 Publications of Boster MIP Antibodies & ELISA Kits
- PubMed ID: 28912850, Effects of leukotriene B4 on interleukin-32, interferon-? and chemokines in rats...
- PubMed ID: 28415997, Mei X, Wang HX, Li JS, Liu XH, Lu XF, Li Y, Zhang WY, Tian YG. BMC Complement Al...
- PubMed ID: 22517906, Bruns I, Cadeddu Rp, Brueckmann I, Fr??bel J, Geyh S, B??st S, Fischer Jc, Roels...
- PubMed ID: 25677765, Sun Y, Zhao Y, Yao J, Zhao L, Wu Z, Wang Y, Pan D, Miao H, Guo Q, Lu N. Biochem ...
- PubMed ID: 26022197, Liu R, An L, Liu G, Li X, Tang W, Chen X. Antiviral Res. 2015 Aug;120:101-11. Do...
*More publications can be found for each product on its corresponding product page