Arylacetamide deacetylase Antibodies

AND AADAC ELISA kits, Arylacetamide deacetylase Proteins

Many biological assays use antibodies to detect Arylacetamide deacetylase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Arylacetamide deacetylase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Arylacetamide deacetylase antibodies...

We validate the specificity of these antibodies to Arylacetamide deacetylase by testing them on tissues known to express AADAC positively and negatively. Browse below to find the AADAC antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AADAC Infographic by Boster Bio

All AADAC Products

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Anti-Arylacetamide deacetylase AADAC Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A06343
100ul

AADAC (NM_001086) Human Over-expression Lysate

Human

$628
Cat # LS000013
100 µg

AADAC Overview

Facts about Arylacetamide deacetylase.

AADAC 3D structure. Source: alphafold

Arylacetamide deacetylase (AADAC)

Displays cellular triglyceride lipase activity in liver, increases the levels of polyunsaturated fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a part in rather low-density lipoprotein assembly. Displays serine esterase activity in liver.

Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. .

Gene Information

Human
Gene Name:	AADAC
Uniprot:	P22760
Entrez:	13

Family

Belongs to:

GDXG' lipolytic enzyme family

Alternative Names

arylacetamide deacetylase (esterase); arylacetamide deacetylase; CES5A1; DACEC 3.1.1.3; EC 3.1.1; EC 3.1.1.79

Molecular Weight

Mass (kDA):
45.734 kDA

Genomic Context


Human

Location:	3q25.1
Sequence:	3; NC_000003.12 (151814008..151828488)

Tissue Specificity

Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein.

Diseases

Hepatotoxicity
Malignant Neoplasm Of Prostate
Malignant Neoplasms
Kidney Failure
Obesity
Liver Carcinoma
Medication Reaction
Methemoglobinemia

Tuberculosis
Diabetes Mellitus

Pathways

Fatty Acid Oxidation
Secretion

PTMs

Deacetylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AADAC

References

PMID: 8063807 by Probst M.R., et al. Human liver arylacetamide deacetylase. Molecular cloning of a novel esterase involved in the metabolic activation of arylamine carcinogens with high sequence similarity to hormone-sensitive lipase.

PMID: 2043131 by Probst M.R., et al. Purification and characterization of a human liver arylacetamide deacetylase.