Product Info Summary
SKU: | A11122 |
---|---|
Size: | 100 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-5-HT-6 HTR6 Antibody
SKU/Catalog Number
A11122
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-5-HT-6 HTR6 Antibody (Catalog # A11122). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-5-HT-6 HTR6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11122)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human 5-HT-6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A11122 is reactive to HTR6 in Human
Reconstitution
Calculated molecular weight
46954 MW
Background of 5-HT6
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
Kohen R., J. Neurochem. 66:47-56(1996).
Kopatz S.A., Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G., Nature 441:315-321(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11122 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from A549 cells, using 5-HT-6 antibody A11122.
Protein Target Info & Infographic
Gene/Protein Information For HTR6 (Source: Uniprot.org, NCBI)
Gene Name
HTR6
Full Name
5-hydroxytryptamine receptor 6
Weight
46954 MW
Superfamily
G-protein coupled receptor 1 family
Alternative Names
5-hydroxytryptamine receptor 6;5-HT-6;5-HT6;Serotonin receptor 6;HTR6; HTR6 5-HT6, 5-HT6R 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 6|5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled|serotonin receptor 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on HTR6, check out the HTR6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for HTR6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-5-HT-6 HTR6 Antibody (A11122)
Hello CJ!
A11122 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Ren S,Chen M,Yang L,Liu Z.5-Hydroxytryptamine and Dopamine Neurons in the Cerebellum of the New-Hatching Yangtze Alligator Alligator sinensis.Anat Rec(Hoboken).2019 Jun;302(6):861-868.doi:10.1002/ar.23982.Epub 2018 Nov 13.PMID:30315688.
Species: Alligators
A11122 usage in article: APP:IHC, SAMPLE:BRAIN TISSUE, DILUTION:1:100
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Customer Q&As
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1 Customer Q&As for Anti-5-HT-6 HTR6 Antibody
Question
Does A11122 contain any Triton X (which has the CAS-No 9002-93-1)?
Verified customer
Asked: 2021-01-06
Answer
Yes, the Anti-5-HT-6 HTR6 Antibody (A11122) contains Triton X (which has the CAS-No 9002-93-1).
Boster Scientific Support
Answered: 2021-01-07