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Product Info Summary
| SKU: | PROTP08476-8 |
|---|---|
| Size: | 5ug,20ug,100ug |
| Origin Species: | Human, Mouse, Rat |
| Source: | Escherichia coli |
| Application: | Cell Culture |
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Product info
Product Name
Human/Mouse/Rat recombinant Activin A protein, AF
View all Activin A recombinant proteins
SKU/Catalog Number
PROTP08476-8
Size
5ug,20ug,100ug
Tag
Tag Free
Description
Activin is the member of the TGF beta superfamily of cytokines. The current understanding of Activin A is classified as a hormone, a Growth Factors, and a cytokine. Depending on the different cell type, that overexpression of Activin A can either inhibit or promote cells division. There are important implications for tumor biology. Activin A also increase joint inflammation in rheumatoid arthritis (RA) and induces pathogenic mechanisms in the respiratory system.
Storage & Handling
Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.
Cite This Product
Human/Mouse/Rat recombinant Activin A protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP08476-8)
Form
Lyophilized
Formulation
The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
Purity
>95% as determined by SDS-PAGE.
Predicted MW
47.442kDa
Molecular weight
The protein has a calculated MW of 13.1 kDa. The protein migrates as 15 kDa under reducing condition (SDS-PAGE analysis).
Activity
Measure by its ability to inhibit the proliferation of mouse MPC-11 cells. The ED₅₀ for this effect is <10 ng/mL. The specific activity of recombinant human Activin A is approximately >1.0 x 10³ IU/mg.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Amino Acid Sequence
GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
Reconstitution
Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.
Assay dilution & Images
Validation Images & Assay Conditions
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SDS- PAGE analysis of recombinant human/mouse/rat Activin A
Protein Target Info & Infographic
Gene/Protein Information For INHBA (Source: Uniprot.org, NCBI)
Gene Name
INHBA
Full Name
Inhibin beta A chain
Weight
47.442kDa
Superfamily
TGF-beta family
Alternative Names
Inhibin beta A chain, Activin beta-A chain, Erythroid differentiation protein INHBA EDF, FRP inhibin subunit beta A inhibin beta A chain|FSH-releasing protein|Inhibin, beta-1|activin beta-A chain|erythroid differentiation factor|erythroid differentiation protein|follicle-stimulating hormone-releasing protein|inhibin beta A subunit|inhibin, beta A (activin A, activin AB alpha polypeptide)
*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".For more info on INHBA, check out the INHBA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for INHBA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].
Specific Publications For Human/Mouse/Rat recombinant Activin A protein, AF (PROTP08476-8)
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