ZNHIT1 Antibodies

AND ZNHIT1 ELISA kits, ZNHIT1 Proteins

Many biological assays use antibodies to detect ZNHIT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZNHIT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZNHIT1 antibodies...

We validate the specificity of these antibodies to ZNHIT1 by testing them on tissues known to express ZNHIT1 positively and negatively. Browse below to find the ZNHIT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNHIT1 Infographic by Boster Bio

All ZNHIT1 Products

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Product

Figures

Specificity

Applications

Price

Anti-ZNHIT1 Antibody

1 Citations 3 Q&As

Human, Mouse

$399
Cat # A12010
100μl

Anti-ZNHIT1 Antibody

Human, Mouse, Rat

$405
Cat # A12010-1
100ul

Human ZNHIT1 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTO43257
Starting from 20ug

ZNHIT1 (NM_006349) Human Over-expression Lysate

Human

$628
Cat # LS010467
100 µg

ZNHIT1 Overview

Facts about Zinc finger HIT domain-containing protein 1.

ZNHIT1 3D structure. Source: alphafold

Zinc finger HIT domain-containing protein 1 (ZNHIT1)

Appears to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity.

Gene Information

Human
Gene Name:	ZNHIT1
Uniprot:	O43257
Entrez:	10467

Family

Belongs to:

ZNHIT1 family

Alternative Names

CG1I; CGBP1; Cyclin-G1-binding protein 1; H_DJ0747G18.14; p18 Hamlet; p18Hamlet; putative cyclin G1 interacting protein; zinc finger HIT domain-containing protein 1; Zinc finger protein subfamily 4A member 1; zinc finger protein, subfamily 4A (HIT domain containing), member 1; zinc finger, HIT domain containing 1; zinc finger, HIT type 1; zinc finger, HIT-type containing 1; ZNFN4A1

Molecular Weight

Mass (kDA):
17.536 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (101218165..101224191)

Tissue Specificity

Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.

Subcellular Localizations

Nucleus.

Diseases

Genotoxic Stress

Interacting Proteins

ACTR6
H2AFZ
KRTAP10-7
MAPK11
MAPK14

TNIP1
TP53BP1

Pathways

Cell Cycle
Cell Cycle Arrest
Cell Proliferation
Cell Death
T Cell Proliferation
Cell Differentiation

PTMs

Phosphorylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNHIT1

References

PMID: 15647280 by Cai Y., et al. The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.

PMID: 17380123 by Cuadrado A., et al. A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis.

1 Publications of Boster ZNHIT1 Antibodies & ELISA Kits

PubMed ID: 10.1016/j.lfs.2019.03.067, Znhit1 inhibits breast cancer by up-regulating PTEN to deactivate the PI3K/Akt/m...

*More publications can be found for each product on its corresponding product page