ZNF207 Antibodies

AND ZNF207 ELISA kits, ZNF207 Proteins

Many biological assays use antibodies to detect ZNF207, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZNF207 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZNF207 antibodies...

We validate the specificity of these antibodies to ZNF207 by testing them on tissues known to express ZNF207 positively and negatively. Browse below to find the ZNF207 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNF207 Infographic by Boster Bio

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ZNF207 (NM_001098507) Human Recombinant Protein

$1062
Cat # PROTO43670
20 µg

ZNF207 Overview

Facts about BUB3-interacting and GLEBS motif-containing protein ZNF207.

ZNF207 3D structure. Source: alphafold

BUB3-interacting and GLEBS motif-containing protein ZNF207 (ZNF207)

Kinetochore- and microtubule-binding protein which plays a key role in spindle assembly (PubMed:24462186, PubMed:24462187, PubMed:26388440). ZNF207/BuGZ is principally composed of disordered low-complexity areas and undergoes phase transition or coacervation to form temperature-dependent liquid droplets.

Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by emphasizing its building blocks (PubMed:26388440). Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3 (PubMed:24462186, PubMed:24462187).

Gene Information

Human
Gene Name:	ZNF207
Uniprot:	O43670
Entrez:	7756

Family

Belongs to:

No superfamily

Alternative Names

DKFZp761N202; zinc finger protein 207

Molecular Weight

Mass (kDA):
50.751 kDA

Genomic Context


Human

Location:	17q11.2
Sequence:	17; NC_000017.11 (32350138..32381885)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Localizes primarily to the nucleus in interphase, concentrates at kinetochores prior to nuclear envelope breakdown and during early prometaphase, and disappears from kinetochores upon microtubule-binding.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF207

References

PMID: 9799612 by Pahl P.M.B., et al. ZNF207, a ubiquitously expressed zinc finger gene on chromosome 6p21.3.

PMID: 24462186 by Jiang H., et al. A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting.