Zinc finger protein ZFPM2 (Zfpm2)

Transcription regulator that plays a central role in heart morphogenesis and growth of coronary vessels from epicardium, by regulating genes that are crucial during cardiogenesis. Essential cofactor that acts through the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6.

Such heterodimer can both activate or repress transcriptional activity, depending upon the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY.