WDR91 Antibodies

AND WDR91 ELISA kits, WDR91 Proteins

Many biological assays use antibodies to detect WDR91, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WDR91 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WDR91 antibodies...

We validate the specificity of these antibodies to WDR91 by testing them on tissues known to express WDR91 positively and negatively. Browse below to find the WDR91 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WDR91 Infographic by Boster Bio

All WDR91 Products

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WDR91 (NM_014149) Human Recombinant Protein

$1062
Cat # PROTA4D1P6
20 µg

WDR91 (NM_014149) Human Over-expression Lysate

Human

$628
Cat # LS029062
100 µg

WDR91 Overview

Facts about WD repeat-containing protein 91.

WDR91 3D structure. Source: alphafold

WD repeat-containing protein 91 (WDR91)

Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes through BECN1, a core subunit of the PI3K complex. By changing the phosphatidylinositol 3-phosphate/PtdInsP3 material of endosomal membranes can regulate endosome fusion, recycling, sorting and early to late endosome transport (PubMed:26783301).

It's for instance, required for the delivery of cargos such as BST2/tetherin from early to late endosome and thereby participates indirectly for their degradation by the lysosome (PubMed:27126989). May play a role in meiosis (By similarity).

Gene Information

Human
Gene Name:	WDR91
Uniprot:	A4D1P6
Entrez:	29062

Family

Belongs to:

WD repeat WDR91 family

Alternative Names

HSPC049; WD repeat domain 91; WD repeat-containing protein 91

Molecular Weight

Mass (kDA):
83.344 kDA

Genomic Context


Human

Location:	7q33
Sequence:	7; NC_000007.14 (135183839..135211556, complement)

Subcellular Localizations

Early endosome membrane; Peripheral membrane protein. Late endosome membrane.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WDR91

References

PMID: 26783301 by Liu K., et al. Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.

PMID: 27126989 by Rapiteanu R., et al. A genetic screen identifies a critical role for the WDR81-WDR91 complex in the trafficking and degradation of tetherin.