VTI1B Antibodies

AND VTI1B ELISA kits, VTI1B Proteins

Many biological assays use antibodies to detect VTI1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VTI1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VTI1B antibodies...

We validate the specificity of these antibodies to VTI1B by testing them on tissues known to express VTI1B positively and negatively. Browse below to find the VTI1B antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VTI1B Infographic by Boster Bio

All VTI1B Products

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Product

Figures

Specificity

Applications

Price

Anti-VTI1b Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A07432
0.1 mg

VTI1B (NM_006370) Human Recombinant Protein

$1249
Cat # PROTQ9UEU0
20 µg

VTI1B (NM_006370) Human Over-expression Lysate

Human

$628
Cat # LS010490
100 µg

VTI1B Overview

Facts about Vesicle transport through interaction with t-SNAREs homolog 1B.

VTI1B 3D structure. Source: alphafold

Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B)

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are suggested to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers.

May be concerned with increased secretion of cytokines associated with cellular senescence. .

Gene Information

Human
Gene Name:	VTI1B
Uniprot:	Q9UEU0
Entrez:	10490

Family

Belongs to:

VTI1 family

Alternative Names

vesicle transport through interaction with t-SNAREs homolog 1B (yeast); Vesicle transport v-SNARE protein Vti1-like 1; vesicle-associated soluble NSF attachment protein receptor; v-SNARE; VTI1; VTI1L; VTI1L1; VTI1-LIKE; Vti1-rp1; VTI2vesicle transport through interaction with t-SNAREs homolog 1B

Molecular Weight

Mass (kDA):
26.688 kDA

Genomic Context


Human

Location:	14q24.1
Sequence:	14; NC_000014.9 (67647085..67674632, complement)

Tissue Specificity

Expressed in all tissues examined.

Subcellular Localizations

Early endosome membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule. Recycling endosome membrane; Single-pass type IV membrane protein.

Diseases

Cystic Fibrosis
Retinal Degeneration
Melanoma
Stomatitis
Familial Hemophagocytic Lymphocytosis
Carcinoma
Edema
Fibrosis
Malignant Neoplasms
Neoplasms
Mammary Neoplasms

Pulmonary Hypertension
Streptococcal Infections
Cell Transformation, Neoplastic
Nerve Degeneration
B16 Malignant Melanoma
Retinitis Pigmentosa

Interacting Proteins

KRTAP10-7
LDLRAD1
PTPN5
STX4
STX8

SYNE4
TRIM59

Pathways

Transport
Membrane Fusion
Localization
Exocytosis
Secretion
Autophagy
Vesicle Transport
Cytokine Secretion
Vesicle Fusion
Phagocytosis
Vesicle Targeting
Secretory Pathway

Cell Killing
Endocytosis
Vesicle Docking
Snare Complex Assembly
Synaptic Vesicle Fusion
Membrane Docking
Oncogenesis

PTMs

Phosphorylation

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VTI1B

References

PMID: 9446565 by Fischer von Mollard G., et al. A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways.

PMID: 9636656 by Li H.-C., et al. A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts.