VPS45 Antibodies

AND VPS45 ELISA kits, VPS45 Proteins

Many biological assays use antibodies to detect VPS45, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VPS45 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VPS45 antibodies...

We validate the specificity of these antibodies to VPS45 by testing them on tissues known to express VPS45 positively and negatively. Browse below to find the VPS45 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VPS45 Infographic by Boster Bio

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VPS45A (VPS45) (NM_007259) Human Over-expression Lysate

Human

$628
Cat # LS011311
100 µg

VPS45 Overview

Facts about Vacuolar protein sorting-associated protein 45.

VPS45 3D structure. Source: alphafold

Vacuolar protein sorting-associated protein 45 (VPS45)

May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. .

Gene Information

Human
Gene Name:	VPS45
Uniprot:	Q9NRW7
Entrez:	11311

Family

Belongs to:

STXBP/unc-18/SEC1 family

Alternative Names

H1; H1VPS45; hlVps45; h-vps45; leucocyte vacuolar protein sorting 45; vacuolar protein sorting 45 homolog (S. cerevisiae); vacuolar protein sorting 45A (yeast homolog); vacuolar protein sorting 45A (yeast); vacuolar protein sorting 45A; vacuolar protein sorting-associated protein 45; VPS45A; VPS45AVPS54A; VPS45B; VSP45; VSP45A

Molecular Weight

Mass (kDA):
65.077 kDA

Genomic Context


Human

Location:	1q21.2
Sequence:	1; NC_000001.11 (150067279..150145329)

Tissue Specificity

Ubiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen, prostate, ovary, small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheral blood leukocytes and liver.

Subcellular Localizations

Golgi apparatus membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Associated with Golgi/endosomal vesicles and the trans-Golgi network.

Diseases

Retinopathy Of Prematurity
Infective Disorder
Neoplasms
Chimera Disorder
Amyotrophic Lateral Sclerosis

Interacting Proteins

RBSN

Pathways

Transport
Membrane Fusion
Localization
Exocytosis
Vesicle Fusion
Hypersensitivity
Secretory Pathway
Protein Transport
Secretion
Endocytosis
Vesicle Docking
Protein Phosphorylation
Regulation Of Vesicle Fusion

Cvt Pathway
Cell Migration
Snare Complex Assembly
Macroautophagy
Interphase
Vesicle Targeting
Vesicle Transport

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VPS45

References

PMID: 8996080 by Pevsner J., et al. Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking.

PMID: 10404641 by Rajasekariah P., et al. Molecular cloning and characterization of a cDNA encoding the human leucocyte vacuolar protein sorting (hlVps45).