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VEGFC Antibodies
AND VEGFC ELISA kits, VEGFC Proteins
Many biological assays use antibodies to detect VEGFC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VEGFC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VEGFC antibodies...
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VEGFC Infographic by Boster Bio
All VEGFC Products
Product
Figures
Specificity
Applications
Price
Human VEGF-C ELISA Kit PicoKine®
16 Citations 8 Q&As
Human
ELISA
$499
Cat # EK0588
96 wells/kit, with removable strips.
Cat # EK0588
96 wells/kit, with removable strips.
Rat
$250
Cat # PROTO35757
2ug, 10ug, 1mg
Cat # PROTO35757
2ug, 10ug, 1mg
VEGFC Overview
Facts about Vascular endothelial growth factor C.
Vascular endothelial growth factor C (VEGFC)
Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of cervical endothelium in adults.
Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors. .
Gene Information
| Human | |
|---|---|
| Gene Name: | VEGFC |
| Uniprot: | P49767 |
| Entrez: | 7424 |
Family
| Belongs to: |
|---|
| PDGF/VEGF growth factor family |
Alternative Names
Flt4 ligand; Flt4-L; vascular endothelial growth factor C; Vascular endothelial growth factor-related protein; VEGFC; VEGF-C; VRPFLT4 ligand DHM
Molecular Weight
Mass (kDA):
46.883 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q34.3 |
| Sequence: | 4; NC_000004.12 (176683538..176792922, complement) |
Tissue Specificity
Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte.
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Neoplasm Metastasis
- Malignant Neoplasms
- Lymphatic Metastasis
- Carcinoma
- Metastatic Malignant Neoplasm To The Lymph Node
- Tumor Angiogenesis
- Cell Invasion
- Pathologic Neovascularization
- Malignant Squamous Cell Neoplasm
- Neoplasm Invasiveness
- Adenocarcinoma
Interacting Proteins
- FLT4
- KDR
Pathways
- Lymphangiogenesis
- Angiogenesis
- Cell Proliferation
- Pathogenesis
- Cell Growth
- Secretion
- Cell Cycle
- Reverse Transcription
- Cell Adhesion
- Wound Healing
- Vasculogenesis
- Tube Formation
- Cell Death
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Angiogenesis
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VEGFC
bosterbio.com/bosterbio-gene-info-cards/VEGFC
References
PMID: 8617204 by Joukov V., et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.
PMID: 8700872 by Lee J., et al. Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.
25 Publications of Boster VEGFC Antibodies & ELISA Kits
- PubMed ID: PMID:30210685, Collagen type V a2 (COL5A2) is decreased in steroid-induced necrosis of the femo...
- PubMed ID: 10.3892/or.2016.4544, IL-6 mediates the signal pathway of JAK-STAT3-VEGF-C promoting growth, invasion ...
- PubMed ID: 10.18632/oncotarget.12449, Lipopolysaccharide increases the release of VEGF-C that enhances cell motility a...
- PubMed ID: 10.1039/C8MT00131F, HER2 and Src co-regulate proliferation, migration and transformation by downstre...
- PubMed ID: 10.1038/srep12807, Down-regulation of HMGB1 expression by shRNA constructs inhibits the bioactivity...
- PubMed ID: 10.1007/s11670-010-0303-5, Interleukin-18 suppresses angiogenesis and lymphangiogenesis in implanted Lewis ...
- PubMed ID: 10.1007/s11010-007-9624-1, RNA interference (RNAi)-mediated vascular endothelial growth factor-C (VEGF-C) r...
- PubMed ID: 10.1002/jcb.22110, Alternatively activated RAW264.7 macrophages enhance tumor lymphangiogenesis in ...
- PubMed ID: , SARI inhibits angiogenesis and tumour growth of human colon cancer through direc...
- PubMed ID: -, Li,X.,Song,D.,Liu,H.,Wang,Z.,Ma,G.,Yu,M. ... Zeng,Y.(2021).Expression levels of ...
- PubMed ID: 31882548, Zhu, G., Lin, C., Cheng, Z., Wang, Q., Hoffman, R. M., Singh, S. R., ... & Ye, J...
- PubMed ID: 17938864 , RNA interference (RNAi)-mediated vascular endothelial growth factor-C (VEGF-C) r...
- PubMed ID: 26239046, Down-regulation of HMGB1 expression by shRNA constructs inhibits the bioactivity...
- PubMed ID: 27713159, Lipopolysaccharide increases the release of VEGF-C that enhances cell motility a...
- PubMed ID: 27353863, SARI inhibits angiogenesis and tumour growth of human colon cancer through direc...
- PubMed ID: 26622898, Expression and clinical significance of microRNA-21, maspin and vascular endothe...
- PubMed ID: 23593080, Chen Y, Wang J, Wang X, Liu X, Li H, Lv Q, Zhu J, Wei B, Tang Y. J Breast Cancer...
- PubMed ID: 19420963, Wang J, Zhao W, Guo Y, Zhang B, Xie Q, Xiang D, Gao J, Wang B, Chen Z. Oncology....
- PubMed ID: 25336971, Song D, Yue W, Li Z, Li J, Zhao J, Zhang N. Onco Targets Ther. 2014 Sep 30;7:180...
- PubMed ID: 22023263, Zhang X, Ding L, Diao Z, Yan G, Sun H, Hu Y. Am J Reprod Immunol. 2012 Mar;67(3)...
- PubMed ID: 22544356, Chuangui C, Peng T, Zhentao Y. Pathol Oncol Res. 2012 Oct;18(4):1021-7. Epub 201...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page