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Versican core protein Antibodies
AND VCAN ELISA kits, Versican core protein Proteins
Many biological assays use antibodies to detect Versican core protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Versican core protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Versican core protein antibodies...
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VCAN Infographic by Boster Bio
All VCAN Products
Product
Figures
Specificity
Applications
Price
Anti-Versican/VCAN Antibody Picoband®
5 Citations 18 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9453
100 μg/vial
Cat # PB9453
100 μg/vial
VCAN Overview
Facts about Versican core protein.
Versican core protein (VCAN)
May play a role in intercellular signaling and in linking cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation.
Binds hyaluronic acid. .
Gene Information
| Human | |
|---|---|
| Gene Name: | VCAN |
| Uniprot: | P13611 |
| Entrez: | 1462 |
Family
| Belongs to: |
|---|
| aggrecan/versican proteoglycan family |
Alternative Names
Chondroitin sulfate proteoglycan 2WGN; Chondroitin sulfate proteoglycan core protein 2; CSPG2; CSPG2DKFZp686K06110; ERVR; GHAP; Glial hyaluronate-binding protein; Large fibroblast proteoglycan; PG-M; PG-MWGN1; VCAN; versican core protein; versican proteoglycan; Versican
Molecular Weight
Mass (kDA):
372.82 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q14.2-q14.3 |
| Sequence: | 5; NC_000005.10 (83471674..83582303) |
Tissue Specificity
Cerebral white matter and plasma. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V2 is restricted to normal brain and gliomas. Isoform V3 is found in all these tissues except medulloblastomas.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix. Cell projection, cilium, photoreceptor outer segment. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
Diseases
- Neoplasms
- Malignant Neoplasms
- Tissue Adhesions
- Malignant Paraganglionic Neoplasm
- Carcinoma
- Headache
- Neoplasm Metastasis
- Inflammation
- Adenocarcinoma
- Nervousness
- Atherosclerosis
- Melanoma
- Cell Invasion
Interacting Proteins
- MMP9
Pathways
- Cell Adhesion
- Localization
- Cell Proliferation
- Pathogenesis
- Regeneration
- Cell Migration
- Cell Differentiation
- Angiogenesis
- Sulfation
- Cell Growth
- Ovulation
- Proteolysis
- Secretion
PTMs
- Cleavage
- Methylation
- Phosphorylation
- Sulphation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VCAN
bosterbio.com/bosterbio-gene-info-cards/VCAN
References
PMID: 2583089 by Zimmermann D.R., et al. Multiple domains of the large fibroblast proteoglycan, versican.
PMID: 7806529 by Dours-Zimmermann M.T., et al. A novel glycosaminoglycan attachment domain identified in two alternative splice variants of human versican.
5 Publications of Boster Versican core protein Antibodies & ELISA Kits
- PubMed ID: 10.2147/OTT.S280309, The Role of CCL20-CCR6 Axis in Ovarian Cancer Metastasis
- PubMed ID: 10.1158/0008-5472.CAN-17-3014, miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2–Ver...
- PubMed ID: 32746997, Liu G,Bai L,Li S,Liu H,Zhu Y,Sun H,Gao S,Jiang W,Li F.Isolation, culture and gro...
- PubMed ID: 27908842, Role of versican and ADAMTS-1 in polycystic ovary syndrome
- PubMed ID: 25915825, Fujii K, Karpova Mb, Asagoe K, Georgiev O, Dummer R, Urosevic-Maiwald M. Leukemi...
*More publications can be found for each product on its corresponding product page