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- Table of Contents
Facts about Vesicle-associated membrane protein 7.
Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.
Human | |
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Gene Name: | VAMP7 |
Uniprot: | P51809 |
Entrez: | 6845 |
Belongs to: |
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synaptobrevin family |
FLJ54296; SYBL1; SYBL1FLJ53762; synaptobrevin-like 1; Synaptobrevin-like protein 1; tetanus neurotoxin-insensitive VAMP; Tetanus-insensitive VAMP; TIVAMP; TI-VAMP; VAMP7; VAMP-7; VAMP-7FLJ53045; vesicle-associated membrane protein 7
Mass (kDA):
24.935 kDA
Human | |
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Location: | Xq28 and Yq12 |
Sequence: | X|Y; NC_000023.11 (155881318..155943769) |
Detected in all tissues tested.
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type IV membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. In immature neurons expression is localized in vesicular structures in axons and dendrites while in mature neurons it is lo
PMID: 8640232 by D'Esposito M., et al. A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation.
PMID: 10655549 by Ciccodicola A., et al. Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.