USP5 Antibodies

Ubiquitin carboxyl-terminal hydrolase 5 (USP5)

Cleaves linear and branched multiubiquitin polymers with a marked taste for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly.

Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 induces the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to contend with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Gene Information

Human
Gene Name:	USP5
Uniprot:	P45974
Entrez:	8078

Family

Belongs to:
peptidase C19 family

Alternative Names

Deubiquitinating enzyme 5; EC 3.1.2.15; EC 3.4.19.12; Isopeptidase T; IsoT; ISOTubiquitin carboxyl-terminal hydrolase 5; ubiquitin isopeptidase T; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5 (isopeptidase T); ubiquitin thioesterase 5; Ubiquitin thiolesterase 5; ubiquitin-specific protease-5 (ubiquitin isopeptidase T); Ubiquitin-specific-processing protease 5; USP5

Molecular Weight

Mass (kDA):
95.786 kDA

Genomic Context

Human
Location:	12p13.31
Sequence:	12; NC_000012.12 (6852138..6866632)

Diseases

• Neoplasms
• Malignant Neoplasms
• Malignant Paraganglionic Neoplasm
• Cell Invasion
• Cell Transformation, Neoplastic
• Neoplasm Metastasis
• Liver Carcinoma
• Glioblastoma
• Malignant Tumor Of Cervix
• Carcinoma
• Cancer Patients And Suicide And Depression
• Virus Diseases

• Patient Dependence On
• Tumor Angiogenesis
• Liver Neoplasms
• Mammary Neoplasms
• Ovarian Neoplasm
• Hyperplasia

Interacting Proteins

• DAZAP2
• RAD23B
• TADA3
• TMEM239

Pathways

• Localization
• Conjugation
• Transport
• Notch Signaling Pathway
• Cell Cycle
• Proteolysis
• Cell Growth
• Angiogenesis
• Protein Ubiquitination

• Rna Splicing
• Nuclear Transport
• Autophagy

PTMs

• Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/USP5

Boster Bio - Best Uses Of The USP5 Marker

If you are interested in learning about the history of Steven Boster, and his favorite marks and firearms, then this article will give you an overview of his life. This article also includes a short biography of Steven Boster. Read on to find out about the most common marks and firearms used by Boster. Listed below are some of Steven Boster's favorite marks and firearms.

Steven Boster's history

You can find all sorts of information about Steve Boster with public records. These records include his current and past addresses, social security numbers, mobile phone numbers, email addresses, and any known relatives. You can even filter this information by age and state. You can also use this information to look up a person by name. There are many historical landmarks in Steven Boster's history. Read on to learn more about the man behind the names.

Steve Boster, aka Steve Boster, passed away on June 26, 2022. He was born in Joliet, IL, to James and Evelyn Meier. He was a former manager in retail sales for many years. He was also a member of Concordia Hall of Staunton, VA. In addition to his two Daughters, Crystal Boster and Natosha Peck, Steve was also survived by six grandchildren. His four brothers, Jack Boster, David Boster, and Sandra Blanton, also survived him. His sisters, Kimberly and Tammy, as well as son Jonathan and granddaughter Cory, reside in Herrin, IL.

His favorite marks

AZMOLA, powder, Warner, and other aforementioned products are among Boster's favourite USP5 marks. Boster scientists can submit results of species, applications, and special samples to Boster and receive product credits. These are valid for scientists around the world. However, Boster scientists are not restricted to the United States. Boster scientists are welcomed to submit their results worldwide. In fact, they can also submit results of other scientists from any country.