USP39 Antibodies

AND USP39 ELISA kits, USP39 Proteins

Many biological assays use antibodies to detect USP39, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USP39 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USP39 antibodies...

We validate the specificity of these antibodies to USP39 by testing them on tissues known to express USP39 positively and negatively. Browse below to find the USP39 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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USP39 Infographic by Boster Bio

All USP39 Products

Product

Figures

Specificity

Applications

Price

Anti-USP39 Antibody

Human, Mouse, Rat

$405
Cat # A06922
100ul

Anti-USP39 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M06922
100 μl/vial

Anti-USP39 Rabbit Monoclonal Antibody

Human, Mouse

IF, IHC, ICC, WB

$370
Cat # M06922-1
100 μl/vial

USP39 (NM_006590) Human Over-expression Lysate

Human

$628
Cat # LS010713
100 µg

USP39 Overview

Facts about U4/U6.U5 tri-snRNP-associated protein 2.

USP39 3D structure. Source: alphafold

U4/U6.U5 tri-snRNP-associated protein 2 (USP39)

Plays a role in pre-mRNA splicing as a part of the U4/U6-U5 tri-snRNP, among the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint.

Doesn't have ubiquitin-specific peptidase activity, but could be a rival of ubiquitin C-terminal hydrolases (UCHs). .

Gene Information

Human
Gene Name:	USP39
Uniprot:	Q53GS9
Entrez:	10713

Family

Belongs to:

peptidase C19 family

Alternative Names

CGI-21; HSPC332; Inactive ubiquitin-specific peptidase 39,65K; SAD1 homolog; SAD1MGC75069; small nuclear ribonucleoprotein 65kDa (U4/U6.U5); SnRNP assembly defective 1 homolog; SNRNP65; U4/U6.U5 tri-snRNP-associated 65 kDa protein; U4/U6.U5 tri-snRNP-associated protein 2; ubiquitin specific peptidase 39; ubiquitin specific protease 39

Molecular Weight

Mass (kDA):
65.381 kDA

Genomic Context


Human

Location:	2p11.2
Sequence:	2; NC_000002.12 (85602843..85649284)

Subcellular Localizations

Nucleus.

Diseases

Microcephaly
Cell Transformation, Neoplastic
Retinoblastoma
Malignant Neoplasms
Neoplasms
Pituitary Diseases

Interacting Proteins

LRRK2

Pathways

Mrna Splicing
Spindle Checkpoint
Cell Cycle
Mitosis
Mrna Processing
Chromosome Segregation
Cytokinesis

Rna Splicing

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/USP39

References

PMID: 11350945 by Makarova O.V., et al. The 65 and 110 kDa SR-related proteins of the U4/U6*U5 tri-snRNP are essential for the assembly of mature spliceosomes.

PMID: 16723661 by Liu S., et al. The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP.