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- Table of Contents
Facts about Ubiquitin carboxyl-terminal hydrolase 1.
Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high action (PubMed:18082604, PubMed:26388029). .
Human | |
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Gene Name: | USP1 |
Uniprot: | O94782 |
Entrez: | 7398 |
Belongs to: |
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peptidase C19 family |
Deubiquitinating Enzyme 1; EC 3.1.2.15; EC 3.4.19.12; hUBP; ubiquitin carboxyl terminal hydrolase 1; Ubiquitin Carboxyl-Terminal Hydrolase 1; ubiquitin specific peptidase 1; ubiquitin specific processing protease 1; ubiquitin specific protease 1; Ubiquitin Thioesterase 1; Ubiquitin thiolesterase 1; Ubiquitin-specific-processing protease 1; UBP; USP1
Mass (kDA):
88.207 kDA
Human | |
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Location: | 1p31.3 |
Sequence: | 1; NC_000001.11 (62436304..62451804) |
Nucleus.
PMID: 9806842 by Fjiwara T., et al. Identification and chromosomal assignment of USP1, a novel gene encoding a human ubiquitin-specific protease.
PMID: 15694335 by Nijman S.M.B., et al. The deubiquitinating enzyme USP1 regulates the Fanconi Anemia pathway.