ULK3 Antibodies

AND ULK3 ELISA kits, ULK3 Proteins

Many biological assays use antibodies to detect ULK3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ULK3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ULK3 antibodies...

We validate the specificity of these antibodies to ULK3 by testing them on tissues known to express ULK3 positively and negatively. Browse below to find the ULK3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ULK3 Infographic by Boster Bio

All ULK3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ULK3 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, IHC-F, ICC, WB

$370
Cat # PB9519
100 μg/vial

Anti-ULK3 Monoclonal Antibody

3 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M07706
100 μl

Anti-ULK3 Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A07706
0.1 mg

ULK3 (NM_001099436) Human Recombinant Protein

$813
Cat # PROTQ6PHR2
20 µg

Anti-ULK3 Antibody (C-term)

Human, Mouse, Rat

$299
Cat # M07706-1
80 µl

ULK3 (NM_001099436) Human Over-expression Lysate

Human

$960
Cat # LS025989
100 µg

ULK3 Overview

Facts about Serine/threonine-protein kinase ULK3.

ULK3 3D structure. Source: alphafold

Serine/threonine-protein kinase ULK3 (ULK3)

Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3).

Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and boosting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.

Gene Information

Human
Gene Name:	ULK3
Uniprot:	Q6PHR2
Entrez:	25989

Family

Belongs to:

protein kinase superfamily

Alternative Names

DKFZP434C131; EC 2.7.11.1; FLJ90566; serine/threonine-protein kinase ULK3; unc-51-like kinase 3 (C. elegans); Unc-51-like kinase 3

Molecular Weight

Mass (kDA):
53.444 kDA

Genomic Context


Human

Location:	15q24.1
Sequence:	15; NC_000015.10 (74836118..74843166, complement)

Tissue Specificity

Widely expressed. Highest levels observed in fetal brain. In adult tissues, high levels in brain, liver and kidney, moderate levels in testis and adrenal gland and low levels in heart, lung, stomach, thymus, prostate and placenta. In the brain, highest expression in the hippocampus, high levels also detected in the cerebellum, olfactory bulb and optic nerve. In the central nervous system, lowest levels in the spinal cord.